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Table 2 Univariate Cox’s proportional hazards model assessing factors associated with mortality after diagnosis of cHCC-CC

From: Combined hepatocellular-cholangiocarcinoma: a population level analysis of incidence and mortality trends

Risk factor

HR*

995% CI

 

P value

Lower

Upper

Race

 Other

Referent

   

 White

1.19

0.88

1.62

0.26(NS)

 Black

1.65

1.07

2.54

0.023

SEER stage

 Localized

Referent

   

 Regional

1.97

1.47

2.63

< 0.001

 Distant

3.09

2.31

4.23

< 0.001

Tumor size, cm

 < 5

Referent

   

 ≥ 5

1.90

1.41

2.56

< 0.001

Treatment

 No surgery

Referent

   

 Surgery

0.22

0.17

0.29

< 0.001

Year of diagnosis

 2000–2004

Referent

   

 2005–2009

0.74

0.57

0.99

0.043

 2010–2014

0.83

0.62

1.10

0.191(NS)

  1. *HRs greater than 1.0 indicate a higher risk of death