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Table 1 Trends in baseline demographic and pathological characteristics of the study population (2000–2014)

From: Combined hepatocellular-cholangiocarcinoma: a population level analysis of incidence and mortality trends

Variable

Total

2000–2004

2005–2009

2010–2014

No. of patients (n)*

642

152

222

268

Median age (years)*

62

63

61

63

Gender, n (%)*

 Women

209(32.6)

59(38.9)

67(30.2)

83(31.0)

 Men

433(67.4)

93(61.1)

155(69.8)

185(69.0)

Race, n (%)*

 White

473(73.7)

108(71.1)

163(73.4)

202(75.4)

 Black

67(10.4)

18(11.8)

15(6.8)

34(12.7)

 Other▲

102(15.9)

26(17.1)

44(19.8)

32(11.9)

SEER historic stage, n (%)*

 Localized

256(39.9)

49(32.3)

98(44.1)

109(40.7)

 Regional

162(25.2)

42(27.6)

54(24.3)

66(24.6)

 Distant

164(25.5)

37(24.3)

51(22.9)

76(28.4)

 Unstaged★

60(9.4)

24(15.8)

19(8.7)

17(6.3)

Grade, n (%)*

 Well differentiated

23(3.6)

6(3.9)

9(4.1)

8(3.0)

 Moderately differentiated

119(18.5)

22(14.5)

38(17.1)

59(22.0)

 Poorly differentiated

193(30.1)

44(28.9)

58(26.1)

91(34.0)

 Undifferentiated

21(3.3)

7(4.6)

6(2.7)

8(3.0)

 Unknown

286(44.5)

73(48.1)

111(50.0)

102(38.0)

  1. *The units are in parentheses
  2. ▲Three patients’ are unknown
  3. ★Fifty-two patient’ stage are unknown