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Table 3 Prognostic factors associated with overall survival

From: Antiviral therapy predicts the outcomes following resection of hepatocellular carcinoma in patients negative for HBV DNA: a propensity score matching analysis

 

Univariate analysis

Multivariate analysis

 

p value

HR

95% CI

p value

HR

95% CI

Gender

0.680

     

Age

0.925

     

AFP

0.403

     

BCLC

0.018

2.320

1.158–4.645

   

Tumor size

0.001

3.875

1.793–8.376

< 0.01

5.092

2.174–11.926

Tumor number

0.066

     

Capsule integrity

0.920

     

Satellite nodule

0.811

     

Vascular invasion

0.017

2.319

1.160–4.639

   

MVI

0.634

     

Necrosis

0.351

     

Liver cirrhosis

0.820

     

PHT

0.365

     

Anatomical hepatectomy

0.044

0.484

0.239–0.981

0.034

0.463

0.227–0.944

Blood loss

0.051

     

Operative time

0.009

3.590

1.379–9.345

< 0.01

7.064

2.433–20.512

ALT

0.986

     

ALB

0.654

     

TB

0.214

     

PT

0.629

     

Antiviral therapy

0.016

0.375

0.168–0.834

   

HBV reactivation

< 0.01

5.353

2.641–10.848

< 0.01

5.190

2.545–10.582

  1. AFP alpha-fetoprotein, BCLC Barcelona clinic liver cancer, MVI microvascular invasion, PHT portal hypertension, ALT alanine aminotransferase, ALB albumin, TB total bilirubin, PT prothrombin time, HBV hepatitis B virus