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Table 1 Study characters of RCTs comparing TP and TR prostate biopsy

From: Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis

Study

Age

Study population

Patients

PSA level

Prostate volume

Biopsy methods

TP group

TR group

TP group

TR group

TP group

TR group

Hara et al., 2008, Japan [21]

71

Patients with a PSA level of 4.0 to 20.0 ng/mL from 2003.5 to 2005.10

126

120

8.34

8.48

33.2

36

Systematic 12-core biopsy

Takenaka et al., 2008, Japan [22]

71 in TP group, 72 in TR group

Consecutive patients with an elevated PSA level (> 4 ng/mL)

100

100

17.1

19.6

34.5

37.2

Systematic 12-core biopsy

Cerruto et al., 2014, Italy [23]

66.5 in TP group, 67.3 in TR group

Consecutive patients with a PSA > 4 ng/mL

54

54

15.95

12.36

56.29

61.49

Systematic 14-core initial prostatic biopsy

Guo et al., 2015, China [20]

67

Patients between 2012.6 and 2014.8 with a PSA > 4.0 ng/ml

173

166

8.81

10.48

47.2

45.9

Systematic 12-core biopsy

  1. Abbreviations: TP transperineal, TR transrectal, PSA prostate-specific antigen