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Table 1 Study characters of RCTs comparing TP and TR prostate biopsy

From: Transperineal versus transrectal prostate biopsy in the diagnosis of prostate cancer: a systematic review and meta-analysis

Study Age Study population Patients PSA level Prostate volume Biopsy methods
TP group TR group TP group TR group TP group TR group
Hara et al., 2008, Japan [21] 71 Patients with a PSA level of 4.0 to 20.0 ng/mL from 2003.5 to 2005.10 126 120 8.34 8.48 33.2 36 Systematic 12-core biopsy
Takenaka et al., 2008, Japan [22] 71 in TP group, 72 in TR group Consecutive patients with an elevated PSA level (> 4 ng/mL) 100 100 17.1 19.6 34.5 37.2 Systematic 12-core biopsy
Cerruto et al., 2014, Italy [23] 66.5 in TP group, 67.3 in TR group Consecutive patients with a PSA > 4 ng/mL 54 54 15.95 12.36 56.29 61.49 Systematic 14-core initial prostatic biopsy
Guo et al., 2015, China [20] 67 Patients between 2012.6 and 2014.8 with a PSA > 4.0 ng/ml 173 166 8.81 10.48 47.2 45.9 Systematic 12-core biopsy
  1. Abbreviations: TP transperineal, TR transrectal, PSA prostate-specific antigen