From: Expression of activator protein-1 in papillary thyroid carcinoma and its clinical significance
Clinical features | n | AP-1 expression [cases (%)] | P value | |
---|---|---|---|---|
Positive | Negative | |||
Gender | ||||
 Male | 17 | 11 (64.7) | 6 (35.3) | 0.184 |
 Female | 65 | 54 (83.1) | 11 (16.9) | |
Age | ||||
 ≥ 55 | 10 | 10 (100) | 0 (0) | 0.19 |
 < 55 | 72 | 55 (76.38) | 17 (23.62) | |
Tumor size | ||||
 ≤ 2 cm | 56 | 40 (71.43) | 16 (28.57) | 0.012 |
 > 2 cm, ≤ 4 cm | 25 | 24 (96) | 1 (4) | |
 > 4 cm | 1 | 1 (100) | 0 (0) | |
Lymph node metastasis | ||||
 Yes | 61 | 50 (82) | 11 (18) | 0.473 |
 No | 21 | 15 (71.4) | 6 (18.6) | |
Multifocality | ||||
 No | 42 | 33 (78.6) | 9 (21.4) | 0.873 |
 Yes | 40 | 32 (80) | 8 (20) | |
Location of lesions | ||||
 Single side | 59 | 48 (81.4) | 11 (18.6) | 0.086 |
 Bilateral | 23 | 17 (73.9) | 6 (26.1) | |
Extrathyroid invasion | ||||
 Yes | 29 | 25 (83.2) | 4 (16.8) | 0.657 |
 No | 53 | 40 (75.5) | 13 (24.5) |