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Table 1 Relationship between AP-1 expression and clinicopathological features in papillary thyroid carcinoma

From: Expression of activator protein-1 in papillary thyroid carcinoma and its clinical significance

Clinical features

n

AP-1 expression [cases (%)]

P value

Positive

Negative

Gender

 Male

17

11 (64.7)

6 (35.3)

0.184

 Female

65

54 (83.1)

11 (16.9)

Age

 ≥ 55

10

10 (100)

0 (0)

0.19

 < 55

72

55 (76.38)

17 (23.62)

Tumor size

 ≤ 2 cm

56

40 (71.43)

16 (28.57)

0.012

 > 2 cm, ≤ 4 cm

25

24 (96)

1 (4)

 > 4 cm

1

1 (100)

0 (0)

Lymph node metastasis

 Yes

61

50 (82)

11 (18)

0.473

 No

21

15 (71.4)

6 (18.6)

Multifocality

 No

42

33 (78.6)

9 (21.4)

0.873

 Yes

40

32 (80)

8 (20)

Location of lesions

 Single side

59

48 (81.4)

11 (18.6)

0.086

 Bilateral

23

17 (73.9)

6 (26.1)

Extrathyroid invasion

 Yes

29

25 (83.2)

4 (16.8)

0.657

 No

53

40 (75.5)

13 (24.5)

  1. Clinical characteristics of patients, and comparisons between expression of AP-1 and tumor size