Table 6 Univariate analysis of characteristics and osteosarcoma patient survival based on the log-rank test
Clinicopathologic data | Case number | Disease-free survival (months) | Overall survival (months) | ||||||
|---|---|---|---|---|---|---|---|---|---|
Mean | SD | 95%CI | P value | Mean | SD | 95%CI | P value | ||
Sex | |||||||||
Male | 38 | 53.81 | 5.59 | 42.85–64.76 | NS | 71.04 | 4.39 | 62.44–79.65 | NS |
Female | 22 | 32.39 | 5.13 | 22.34–42.44 | 53.81 | 6.59 | 40.91–66.72 | ||
Age (years) | |||||||||
< 18 | 26 | 37.42 | 5.43 | 26.79–48.06 | NS | 51.51 | 4.42 | 42.84–60.17 | NS |
≥ 18 | 34 | 51.96 | 5.91 | 40.37–63.54 | 68.56 | 5.00 | 58.75–78.36 | ||
Tumor location | |||||||||
Tibia or femur | 40 | 49.67 | 5.56 | 38.77–60.57 | NS | 67.47 | 4.52 | 58.60–76.33 | NS |
Other location | 20 | 46.15 | 7.57 | 31.32–60.98 | 60.55 | 6.86 | 47.10–74.00 | ||
Histologic subtype | |||||||||
Conventional | 55 | 49.20 | 4.77 | 39.86–58.54 | NS | 66.42 | 3.97 | 58.64–74.20 | NS |
Special | 5 | 40.20 | 10.96 | 18.71–61.69 | 55.40 | 14.72 | 26.54–84.26 | ||
Tumor size (cm) | |||||||||
< 5 | 23 | 65.17 | 6.63 | 52.18–78.17 | 0.006 | 77.91 | 4.36 | 69.38–86.45 | 0.015 |
≥ 5 | 37 | 36.39 | 4.97 | 26.65–46.12 | 55.98 | 4.96 | 46.26–65.71 | ||
Enneking staging | |||||||||
I-IIA | 21 | 70.05 | 6.27 | 57.75–82.34 | 0.001 | 79.71 | 4.25 | 71.39–88.04 | 0.010 |
IIB | 39 | 36.42 | 5.08 | 26.46–46.38 | 56.54 | 4.87 | 47.00–66.07 | ||
Response to chemotherapya | |||||||||
Good | 28 | 63.86 | 6.14 | 51.83–75.89 | 0.002 | 79.11 | 3.76 | 71.74–86.48 | 0.001 |
Poor | 32 | 32.84 | 4.91 | 23.22–42.47 | 51.56 | 5.42 | 40.94–62.18 | ||