Clinicopathological and prognostic values of fibronectin and integrin αvβ3 expression in primary osteosarcoma

Table 3 Association between individual FN and αvβ3 expression and clinicopathological characteristics in osteosarcoma

Clinicopathologic data	Case number	FN			αvβ3
Clinicopathologic data	Case number	High (n = 19)	Low/Neg (n = 41)	P value	High (n = 16)	Low/Neg (n = 44)	P value
Sex
Male	38	11	27	NS	9	29	NS
Female	22	8	14		7	15
Age (years)
< 18	26	6	20	NS	8	18	NS
≥ 18	34	13	21		8	26
Tumor size (cm)
< 5	23	6	17	NS	4	19	NS
≥ 5	37	13	24		12	25
Tumor location
Tibia or femur	40	11	25	NS	11	29	NS
Other location	20	4	16		5	15
Histologic subtype
Conventional	55	17	38	NS	14	41	NS
Special	5	2	3		2	3
Enneking staging
I-IIA	21	4	17	NS	2	19	0.028
IIB	39	15	24		14	25
Response to chemotherapy^a
Good	28	3	25	0.001	2	26	0.002
Poor	32	16	16		14	19

ISSN: 1477-7819