Fig. 3

Kaplan-Meier analyses of disease-free survival (DFS) and overall survival (OS) time by FN and αvβ3 expression. a, b Significant differences in DFS (P < 0.001) and OS (P < 0.001) time were observed between high FN expression (FN⁺) and low/negative FN expression (FN⁻) groups. c, d Significant differences in DFS (P < 0.001) and OS (P < 0.001) time were observed between high αvβ3 expression (αvβ3⁺) and low/negative αvβ3 expression (αvβ3⁻) groups. e, f Significant differences in DFS (P < 0.001) and OS (P < 0.001) time were demonstrated between FN⁺/αvβ3⁺ and “others” groups. g A significant difference in DFS (P < 0.001) time was demonstrated between FN⁺/αvβ3⁺ and FN⁻/αvβ3⁻ groups. h Significant differences in OS time were demonstrated between FN⁺/αvβ3⁺ and FN⁻/αvβ3⁻ groups (P < 0.001) and between FN⁺/αvβ3⁺ and “others” groups (P = 0.005). *, “others” included the single high-expression and double low/negative-expression groups (FN⁺/αvβ3⁻ plus FN⁻/αvβ3⁺ plus FN⁻/αvβ3⁻); †, “others” included the single high-expression groups (FN⁺/αvβ3⁻ plus FN⁻/αvβ3⁺)