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Table 2 Assessment of clinicopathological parameters predicting progression-free survival on univariate and multivariate analyses

From: Abundance of mitochondrial superoxide dismutase is a negative predictive biomarker for endometriosis-associated ovarian cancers

   

PFS univariate

PFS multivariate

  

n

HR (95% CI)

p value

HR (95% CI)

p value

Age

60</≤60

11/50

0.4890 (0.105–2.289)

0.3632

  

FIGO class

III, IV/I, II

10/51

30.303 (7.353–125)

< 0.0001

19.608 (5.952–66.667)

< 0.0001

Blood marker

Positive/negative

48/13

0.806 (0.204–3.185)

0.7583

  

Histology

Clear cell/endometrioid

41/20

2.212 (0.5778–8.475)

0.2463

  

Standard treatment

Incomplete/complete

8/53

6.410 (1.488–27.778)

0.0126

7.576 (1.828–31.25)

0.0052

SOD2 expression

High/low

46/15

17.543 (1.825–166.667)

0.0130

10 (1.271–76.923)

0.0287

  1. On univariate analysis, high expression of mitochondrial superoxide dismutase (SOD2), incompleteness of standard treatment, and high International Federation of Gynecology and Obstetrics (FIGO) stage were associated with poor prognosis. Multivariate Cox proportional hazards analysis also confirmed that high SOD2 expression, incompleteness of standard treatment, and high FIGO stage were significant prognostic factors for worse progression-free survival (PFS). CI confidence interval, HR hazards ratio