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Table 4 Association between clinical characteristics of patients with bladder cancer and rs2292016

From: The role of oncostatin M receptor gene polymorphisms in bladder cancer

Characteristics

Cases No.

Genotype No. (%)

P value

Allele No. (%)

P value

OR (95%CI)

GG

GT

TT

G

T

Gender

 Male

241 (78.8)

104 (43.1)

108 (44.8)

29 (12.0)

0.43

316 (65.6)

166 (34.4)

0.34

1.23 (0.81–1.87)

 Female

65 (21.2)

32 (49.2)

27 (41.5)

6 (9.2)

91 (70.0)

39 (30.0)

Age

 ≤ 64

139 (45.4)

61 (43.9)

63 (45.3)

15 (10.8)

0.65

185 (66.5)

93 (33.5)

0.98

0.99 (0.71–1.40)

 > 64

167 (54.6)

75 (44.9)

72 (43.1)

20 (12.0)

222 (66.5)

112 (33.5)

Smoking status

 Non-smokers

147 (48.0)

65 (44.2)

62 (42.2)

20 (13.6)

0.35

192 (65.3)

102 (34.7)

0.55

1.11 (0.79–1.55)

 Smokers

159 (52.0)

71 (44.6)

73 (45.9)

15 (9.4)

215 (67.6)

103 (32.4)

Stage

 NMIBC

164 (53.6)

75 (45.7)

69 (42.1)

20 (12.2)

0.72

219 (66.8)

109 (33.2)

0.88

0.98 (0.70–1.37)

 MIBC

142 (46.4)

61 (43.0)

66 (46.5)

15 (10.6)

188 (66.2)

96 (33.8)

Grade

 Low

132 (43.1)

65 (49.2)

47 (35.6)

20 (15.2)

0.009

177 (67.0)

87 (33.0)

0.81

0.96 (0.68–1.35)

 High

174 (56.9)

71 (40.8)

88 (50.6)

15 (8.6)

230 (66.1)

118 (33.9)

Recurrence

 Negative

217 (70.9)

106 (48.9)

88 (40.5)

23 (10.6)

0.036

300 (69.1)

134 (30.9)

0.032

0.67 (0.47–0.97)

 Positive

89 (29.1)

30 (33.7)

47 (52.8)

12 (13.5)

107 (60.1)

71 (39.9)

  1. Values in italics are statistically significant