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Table 1 Characteristics of the trials

From: Perioperative transfusion and the prognosis of colorectal cancer surgery: a systematic review and meta-analysis

ID Country Tumour type Sample size Transfusion trigger Type of blood products Outcomes NOS (stars)
BT+ BT− Total
1 Tarantino I 2013 [1] Switzerland Colonic 148 161 309 OS 7
2 Gunka I 2013 [2] Czech Colorectal 132 451 583 OS 7
3 Amri R 2017 [3] USA Colonic 305 1118 1423 OS, CSS 8
4 Morner MEM 2016 [4] Sweden Colorectal 199 297 496 OS 8
5 Qiu L 2015 [8] China Colorectal 803 601 1404 Hb < 6 g/dL, Hb 6–10 g/dL according to cardiopulmonary function OS, postoperative complications 7
6 Miki C 2006 [9] Japan Colorectal 35 82 117 OS, postoperative complications 8
7 Meng J 2013 [10] China Colonic 259 211 470 Hb < 8 g/dL OS, postoperative complications 7
8 Talukder Y 2014 [11] Australia Colorectal 423 947 1370 OS, DFS, CSS, postoperative complications 8
9 Due SL 2012 [12] Australia Colorectal 151 654 805 CSS, postoperative complications 7
10 Jagoditsch M 2006 [13] Australia Rectal 471 126 597 Preoperative Hb < 8 g/dL, intraoperative bleeding > 500 mL or Hb < 10 g/dL OS, DFS, postoperative complications 7
11 Lobaziewicz W 2008 [14] Poland Colorectal 122 135 257 Intraoperative bleeding > 1000 mL or Hct < 30% RBC OS, CSS, DFS 8
12 Kaneko M 2015 [15] Japan Colorectal 23 85 108 Allogeneic red blood cell OS 8
13 Nursal TZ 2006 [16] Turkey Colorectal 61 272 333 Whole blood or RBC OS 7
14 Li XX 2015 [17] China Colonic 614 461 1075 Hb < 6 g/dL, Hb 6–10 g/dL according to cardiopulmonary function OS, postoperative complications 7
15 Halabi WJ 2013 [18] USA Colorectal 3815 23,305 27,120 RBC OS, postoperative complications 8
16 Warschkow R 2014 [19] Switzerland Rectal 217 184 401 Prestored allogeneic blood OS, DFS 7
17 Koch M 2011 [20] Germany Colorectal 135 396 531 Hb 8–10 g/dL according to cardiopulmonary function Postoperative complications 7
18 Ghinea R 2013 [21] Italy Colorectal 68 133 201 OS, DFS, postoperative complications 7
19 Skanberg J 2007 [22] Sweden Colorectal 298 344 642 LDB or RBC OS 8
20 Mynster T 2000 [23] Denmark Colorectal 288 452 770 SAGM and/or FFP Postoperative complications 8
21 Patel SV 2017 [24] Canada Colonic 2009 5189 7198 OS, CSS 9
22 van de Watering LMG2001 [25] Netherlands Colorectal 446 251 697 LDB or RBC OS 7
23 Papageorge CM 2016 [26] England Colorectal 2073 58,712 72,011 Whole blood or RBC Postoperative complications 7
24 Benoist S 2001 [27] France Rectal 72 140 212 Hb < 8 g/dL Postoperative complications 7
25 Jensen LS 2005 [28] Denmark Colorectal 249 320 569 LDB or RBC OS, postoperative complications 9
26 Mynster T 2001 [29] Denmark Colorectal 452 288 740 SAGM and/or FFP OS 7
27 Aquina CT 2016 [30] USA Colorectal 6927 17,303 24,230 OS, CSS, postoperative complications 8
28 Mazzeffi M 2017 [31] USA Colonic 1845 23,388 24,733 RBC Postoperative complications 8
29 Van Osdol AD 2015 [32] USA Colorectal 110 365 475 Postoperative Hb < 7 g/dL, preoperative Hb < 8.4 g/dL OS, DFS, postoperative complications 7
30 Sánchez-Velázquez P 2018 [33] Spain Colonic    363 DFS, CSS 8
31 Molland G 1995 [34] Australia Colorectal 223 210 433 All kinds of blood products OS 8
32 Cheslyn-Curtis S 1990 [35] UK Colorectal 591 370 961 OS 7
33 Donohue JH 1995 [36] USA Colorectal 446 605 1051 Whole blood or RBC or plasma OS 8
34 Tartter PI 1992 [37] USA Colorectal 110 229 329 RBC DFS 7
35 Garau I 1994 [38] Spain Colorectal 348 338 686 Whole blood or RBC or plasma OS 7
36 Edna TH 1994 [39] Norway Colorectal 236 100 336 Hb < 9 g/dL or bleeding > 20% blood volume SAGM OS 8
  1. LDB leucocyte-depleted blood products, RBC packed red blood cells, SAGM buffy coat-depleted red cells suspended in saline, adenine, glucose, and mannitol, FFP fresh-frozen plasma