Specific risk factors contributing to early and late recurrences of intrahepatic cholangiocarcinoma after curative resection

Table 3 Multivariate analysis of factors related to early recurrence

Variable	HR	95% CI	P value
Microvascular invasion
Yes vs. no	2.084	1.115–3.897	0.021
Tumor number
Multiple vs. single	2.071	1.185–3.616	0.010
CA19-9 (U/L)
> 37 vs. ≤ 37	1.619	1.076–2.437	0.021
HBV infection
Positive vs. negative	1.650	1.123–2.427	0.011

Abbreviations: CA19-9 carbohydrate antigen 19-9, HBV hepatitis B virus. There were statistically significant differences for data in Italics (p < 0.05)

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