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Table 2 Linear regression analysis between clinicopathologic characteristics and normalized SLC7 family gene expression in thyroid cancer patients

From: Upregulation of the solute carrier family 7 genes is indicative of poor prognosis in papillary thyroid carcinoma

Gene

Age

Tumor size

Gender (male)

Absence of thyroiditis

Absence of ETE

AJCC stage (III/IV)

BRAF mutation

RAS mutation

Mortality

SLC7A1

      

++

  

SLC7A2

   

  

+++

  

SLC7A3

   

++

+

++

 

+

SLC7A4

      

+++

−−−

 

SLC7A5

        

+

SLC7A6

      

−−−

+++

 

SLC7A7

   

+++

     

SLC7A8

   

−−

−−

+

−−

 

SLC7A9

   

++

 

−−−

  

SLC7A10

         

SLC7A11

     

   

SLC7A13

         

SLC7A14

      

  
  1. +, positive correlation with P value < .05; ++, positive correlation with P value < .01; +++, positive correlation with P value < .001
  2. −, negative correlation with P value < .05; −, negative correlation with P value < .01; −−, negative correlation with P value < .001