From: Prognostic significance of sealed-off perforation in colon cancer: a prospective cohort study
Free perforation (n = 24) | Sealed-off perforation (n = 62) | p value | |
---|---|---|---|
Age (years old) | 76.1 ± 12.5 | 59.4 ± 15.5 | 0.000 |
Sex | 0.874 | ||
Male | 14 (58.3%) | 35 (56.5%) | |
Female | 10 (41.7%) | 27 (43.5%) | |
BMI (kg/m2) | 22.7 ± 3.5 | 22.0 ± 2.8 | 0.458 |
ASA class | 0.001 | ||
1 | 4 (19.0%) | 26 (44.8%) | |
2 | 8 (38.1%) | 26 (44.8%) | |
3 | 8 (38.1%) | 6 (10.3%) | |
4 | 1 (4.8%) | 0 (0%) | |
Surgery | 0.000 | ||
Elective | 2 (8.3%) | 48 (77.4%) | |
Emergency | 22 (91.7%) | 14 (22.6%) | |
Operation intent | 0.752 | ||
Curative | 19 (79.2%) | 52 (83.9%) | |
Palliative | 5 (20.8%) | 10 (16.1%) | |
Tumor differentiation | 0.858 | ||
Adenocarcinoma, well differentiated | 1 (4.2%) | 3 (4.8%) | |
Adenocarcinoma, moderate differentiated | 19 (79.2%) | 48 (77.4%) | |
Adenocarcinoma, poorly differentiated | 3 (12.5%) | 8 (12.9%) | |
Mucinous carcinoma | 1 (4.2%) | 2 (3.2%) | |
Signet ring cell carcinoma | 0 (0.0%) | 1 (1.6%) | |
Size (cm) | 5.8 ± 2.3 | 6.6 ± 2.3 | 0.100 |
pT | 0.687 | ||
3 | 12 (50.0%) | 28 (45.2%) | |
4 | 12 (50.0%) | 34 (54.8%) | |
pN | 0.779 | ||
0 | 10 (41.7%) | 27 (43.5%) | |
1 | 11 (45.8%) | 23 (37.1%) | |
2 | 3 (12.5%) | 12 (19.4%) | |
The number of metastatic LN | 1.5 ± 2.9 | 2.2 ± 3.8 | 0.325 |
The number of harvest LN | 18.9 ± 9.5 | 23.3 ± 11.4 | 0.091 |
M | 0.588 | ||
0 | 16 (66.7%) | 45 (72.6%) | |
1 | 8 (33.3%) | 17 (27.4%) | |
Proximal margin (cm) | 27.5 ± 30.2 | 19.5 ± 20.4 | 0.088 |
Distal margin (cm) | 13.9 ± 14.5 | 10.7 ± 9.5 | 0.395 |
Lymphatic invasion | 0.848 | ||
Absent | 13 (54.2%) | 35 (56.5%) | |
Present | 11 (45.8%) | 27 (43.5%) | |
Venous invasion | 0.161 | ||
Absent | 15 (62.5%) | 45 (77.6%) | |
Present | 9 (37.5%) | 13 (22.4%) | |
Perineural invasion | 0.541 | ||
Absent | 17 (70.8%) | 37 (63.8%) | |
Present | 7 (29.2%) | 21 (36.2%) | |
Postoperative complication | |||
(Clavien-Dindo classification) | 0.000 | ||
No complication | 9 (37.5%) | 50 (42.5%) | |
Grade I | 2 (8.3%) | 0 (0%) | |
Grade II | 4 (16.7%) | 8 (12.9%) | |
Grade III | 5 (20.8%) | 3 (4.8%) | |
Grade IV | 4 (16.7%) | 1 (1.6%) | |
Postoperative chemotherapy | 7 (29.2%) | 46 (74.2%) | 0.000 |