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Table 1 Baseline characteristics

From: Prognostic significance of sealed-off perforation in colon cancer: a prospective cohort study

  Free perforation (n = 24) Sealed-off perforation (n = 62) p value
Age (years old) 76.1 ± 12.5 59.4 ± 15.5 0.000
Sex    0.874
 Male 14 (58.3%) 35 (56.5%)  
 Female 10 (41.7%) 27 (43.5%)  
BMI (kg/m2) 22.7 ± 3.5 22.0 ± 2.8 0.458
ASA class    0.001
 1 4 (19.0%) 26 (44.8%)  
 2 8 (38.1%) 26 (44.8%)  
 3 8 (38.1%) 6 (10.3%)  
 4 1 (4.8%) 0 (0%)  
Surgery    0.000
 Elective 2 (8.3%) 48 (77.4%)  
 Emergency 22 (91.7%) 14 (22.6%)  
Operation intent    0.752
 Curative 19 (79.2%) 52 (83.9%)  
 Palliative 5 (20.8%) 10 (16.1%)  
Tumor differentiation    0.858
 Adenocarcinoma, well differentiated 1 (4.2%) 3 (4.8%)  
 Adenocarcinoma, moderate differentiated 19 (79.2%) 48 (77.4%)  
 Adenocarcinoma, poorly differentiated 3 (12.5%) 8 (12.9%)  
 Mucinous carcinoma 1 (4.2%) 2 (3.2%)  
 Signet ring cell carcinoma 0 (0.0%) 1 (1.6%)  
Size (cm) 5.8 ± 2.3 6.6 ± 2.3 0.100
pT    0.687
 3 12 (50.0%) 28 (45.2%)  
 4 12 (50.0%) 34 (54.8%)  
pN    0.779
 0 10 (41.7%) 27 (43.5%)  
 1 11 (45.8%) 23 (37.1%)  
 2 3 (12.5%) 12 (19.4%)  
The number of metastatic LN 1.5 ± 2.9 2.2 ± 3.8 0.325
The number of harvest LN 18.9 ± 9.5 23.3 ± 11.4 0.091
M    0.588
 0 16 (66.7%) 45 (72.6%)  
 1 8 (33.3%) 17 (27.4%)  
Proximal margin (cm) 27.5 ± 30.2 19.5 ± 20.4 0.088
Distal margin (cm) 13.9 ± 14.5 10.7 ± 9.5 0.395
Lymphatic invasion    0.848
 Absent 13 (54.2%) 35 (56.5%)  
 Present 11 (45.8%) 27 (43.5%)  
Venous invasion    0.161
 Absent 15 (62.5%) 45 (77.6%)  
 Present 9 (37.5%) 13 (22.4%)  
Perineural invasion    0.541
 Absent 17 (70.8%) 37 (63.8%)  
 Present 7 (29.2%) 21 (36.2%)  
Postoperative complication    
(Clavien-Dindo classification)    0.000
 No complication 9 (37.5%) 50 (42.5%)  
 Grade I 2 (8.3%) 0 (0%)  
 Grade II 4 (16.7%) 8 (12.9%)  
 Grade III 5 (20.8%) 3 (4.8%)  
 Grade IV 4 (16.7%) 1 (1.6%)  
Postoperative chemotherapy 7 (29.2%) 46 (74.2%) 0.000
  1. BMI body mass index, ASA class American Society of Anesthesiologists classification, LN lymph nodes