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Table 7 The results of ROC curve analysis

From: Suppressor of cytokine signaling (SOCS) genes are downregulated in breast cancer

 

Estimate criterion

AUC

J a

Sensitivity

Specificity

P valueb

SOCS1

> 2.7

0.6

0.2

40.7

79.6

0.05

SOCS2

> − 2.4

0.64

0.25

88.9

37

0.007

SOCS3

> − 0.9

0.63

0.24

72.2

51.9

0.01

SOCS5

> − 0.8

0.67

0.25

75.9

50

0.0009

Combination of all genes

≤ 0.5

0.68

0.35

64.8

70.4

0.0004

  1. Estimate criterion: optimal cutoff point for gene expression
  2. aYouden index,
  3. bSignificance level P (area = 0.5)