Table 3 The results of association analysis between relative expressions of genes in tumoral tissues compared with ANCTs and patients’ clinicopathological data (up/downregulation of genes was defined based on relative expression of each gene in tumoral tissue compared with the paired ANCT)
From: Assessment of expression of interferon γ (IFN-G) gene and its antisense (IFNG-AS1) in breast cancer
IFNG upregulation | IFNG downregulation | P value | IFNG-AS1 upregulation | IFNG-AS1 downregulation | P value | |
|---|---|---|---|---|---|---|
Age | 0.63 | 0.5 | ||||
< 40 | 8 (67.6%) | 3 (27.3%) | 9 (81.8%) | 2 (18.2%) | ||
40–50 | 10 (58.2%) | 7 (41.2%) | 11 (64.7%) | 6 (35.3%) | ||
51–60 | 10 (76.9%) | 3 (23.1%) | 10 (76.9%) | 3 (23.1%) | ||
61–70 | 5 (62.5%) | 3 (37.5%) | 5 (62.5%) | 3 (37.5%) | ||
> 71 | 2 (40%) | 3 (60%) | 2 (40%) | 3 (60%) | ||
Stage | 0.95 | 0.25 | ||||
1 | 9 (56.3%) | 7 (43.7%) | 10 (62.5%) | 6 (37.5%) | ||
2 | 10 (66.7%) | 5 (33.3%) | 9 (60%) | 6 (40%) | ||
3 | 11 (68.8%) | 5 (31.2%) | 14 (87.5%) | 2 (12.5%) | ||
4 | 4 (80%) | 1 (20%) | 3 (20%) | 2 (80%) | ||
Histological grade | 0.87 | 0.91 | ||||
1 | 5 (62.5%) | 3 (37.5%) | 6 (75%) | 2 (25%) | ||
2 | 16 (69.6%) | 7 (30.4%) | 15 (62.5%) | 8 (34.8%) | ||
3 | 10 (62.5%) | 6 (37.5%) | 12 (75%) | 4 (25%) | ||
Mitotic rate | 0.9 | 0.64 | ||||
1 | 13 (68.4%) | 6 (31.6%) | 14 (73.7%) | 5 (26.3%) | ||
2 | 11 (61.1%) | 7 (38.9%) | 11 (61.1%) | 7 (38.9%) | ||
3 | 3 (60%) | 2 (40%) | 4 (80%) | 1 (20%) | ||
Tumor size | 0.7 | 0.67 | ||||
< 2 | 9 (56.3%) | 7 (43.7%) | 12 (75%) | 4 (25%) | ||
2–5 | 22 (66.7%) | 11 (33.3%) | 21 (63.6%) | 12 (36.4%) | ||
> 5 | 1 (100%) | 0 (0%) | 1 (100%) | 0 (0%) | ||
ER status | 0.08 | 0.65 | ||||
Positive | 26 (60.5%) | 17 (39.5%) | 29 (67.4%) | 14 (32.6%) | ||
Negative | 6 (100%) | 0 (0%) | 5 (16.7%) | 1 (83.3%) | ||
PR status | 0.07 | 0.46 | ||||
Positive | 22 (59.5%) | 15 (40.5%) | 25 (67.6%) | 12 (32.4%) | ||
Negative | 10 (90.9%) | 1 (9.1%) | 9 (81.8%) | 2 (18.2%) | ||
HER2 status | 0.48 | 0.27 | ||||
Positive | 7 (58.3%) | 5 (41.7%) | 7 (58.3%) | 5 (41.7%) | ||
Negative | 25 (69.4%) | 11 (30.6%) | 27 (75%) | 9 (25%) | ||