Ability of the ALBI grade to predict posthepatectomy liver failure and long-term survival after liver resection for different BCLC stages of HCC

Table 2 Multivariate logistic regression analyses for posthepatectomy liver failure across BCLC stages

Variable	Multivariate logistic regression
	Total cohort		BCLC 0/A		BCLC B/C
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Prothrombin time > 14 s	1.19 (0.39–3.63)	0.765	1.39 (0.35–5.47)	0.635	0.48 (0.04–6.60)	0.584
Platelet count < 100 × 10⁹/l	2.82 (0.97–8.19)	0.056	0.45 (0.07–2.94)	0.405	132.70 (6.04–916.91)	0.002
Tumor size > 5 cm	0.65 (0.21–2.01)	0.456	0.50 (0.11–2.23)	0.361	0.49 (0.04–6.52)	0.587
ALBI score > −2.44	3.43 (1.11–10.57)	0.032	2.33 (1.09–9.19)	0.046	30.48 (1.36–682.73)	0.031
Child-Pugh score > 6	6.47 (2.10–19.94)	0.001	5.50 (1.23–24.50)	0.025	43.21 (2.43–767.29)	0.010
Blood loss > 400 ml	2.13 (0.83–5.44)	0.115	1.75 (0.55–5.57)	0.346	5.86 (0.53–64.72)	0.149
Major hepatectomy	5.51 (1.86–16.29)	0.002	7.23 (1.73–30.57)	0.007	12.02 (0.97–149.04)	0.053
MELD score > 8	0.67 (0.21–2.11)	0.496	0.90 (0.21–3.78)	0.885	0.35 (0.03–3.62)	0.378

OR odds ratio, CI confidence interval, BCLC Barcelona Clinic Liver Cancer, ALBI albumin-bilirubin, MELD model for end-stage liver disease