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Table 4 Comparison of estimates of recurrence between those with early and late recurrence using group LASSO analysis

From: Introducing novel and comprehensive models for predicting recurrence in breast cancer using the group LASSO approach: are estimates of early and late recurrence different?

Variables

Recurrence

< 5 years

> 5 years

Odds ratio

95% CI

Odds ratio

95% CI

Age

0.96*

0.95–0.97

1.00

0.99–1.01

Number of pregnancies

0.94*

0.89–0.99

0.96

0.91–1.00

Family history of other cancers

0.73*

0.60–0.89

1.00

0.85–1.17

Hormone therapy

0.76*

0.61–0.96

1.00

0.83–1.20

Total lymph nodes dissected

0.98*

0.97–0.99

1.00

0.99–1.01

Right-sided breast involvement

0.87*

0.77–0.99

1.00

0.89–1.13

Diabetes

0.77*

0.60-0.98

1.00

0.83–1.21

History of breast operation

0.38*

0.17–0.88

1.00

0.65–1.53

Sports activity

0.79

0.60–1.05

1.00

0.68–1.47

Regular sports activity†

0.80

0.57–1.13

1.00

0.80–1.24

Sports duration

1.00

0.95–1.05

1.00

0.81–1.24

Number of abortions

1.04

0.95–1.14

1.00

0.87–1.14

Number of children

1.00

0.96–1.04

1.00

0.98–1.02

Duration of breast feeding

1.00

1.00–1.00

1.00

1.00–1.00

Hormone replacement therapy

1.04

0.41–2.63

1.00

0.63–1.60

Family history of breast cancer

1.00

0.86–1.17

1.00

0.53–1.87

Waterpipe use

1.00

0.72–1.39

1.00

0.96–1.04

Smoking

5.72*

2.11-15.55

1.32

1.00–1.73

History of breast disease

3.32*

1.92–5.76

1.00

0.56–1.79

In situ component

1.58*

1.35–1.84

1.00

0.91–1.10

Tumor necrosis

1.87*

1.57–2.22

1.00

0.85–1.17

Axillary management‡

 Sentinel lymph node biopsy

2.90*

2.05–4.11

1.00

0.67–1.48

 both

3.50*

2.26-5.42

1.00

0.63–1.58

 No axillary management

0.81

0.63–1.05

1.01

0.80–1.29

 Grade 3§

1.79*

1.46–2.21

1.00

0.82–1.22

Staging of breast cancer||

 Stage 1

1.16

0.95–1.42

0.97

0.81–1.16

 Stage 2

2.71*

2.18–3.35

1.67*

1.31-2.14

 Stages 3 and 4

5.01*

3.52–7.13

1.31

0.83–2.05

Radiotherapy¶

 Yes with mastectomy

2.97*

2.39–3.68

2.45*

1.81-3.32

 Yes with breast conserving surgery

2.50*

2.00–3.12

1.75*

1.32-2.32

 No with breast conserving surgery

17.58*

6.70–46.10

7.62*

1.52-38.15

Invasive LN in dissection

1.00

0.99–1.01

1.00

0.98–1.01

Chemotherapy before surgery

1.00

0.83–1.20

0.76

0.54–1.07

Chemotherapy after surgery

1.00

0.66–1.50

1.00

0.72–1.39

Tumor size

1.02

0.98–1.07

0.97

0.93–1.01

  1. *Shows statistical significance (p < 0.05)
  2. †Irregular sports activity was considered base for comparison
  3. ‡Having axillary lymph node dissection was considered base for comparison
  4. §Grades 1 and 2 were considered base for comparison
  5. ||Stage zero was considered base for comparison
  6. ¶Having mastectomy without radiotherapy was considered base for comparison