Table 1 Baseline and clinicopathological characteristics of individuals with and without recurrence*
Variables | Recurrence | Overall (n = 1273) | p value | |
|---|---|---|---|---|
Yes (n = 712) | No (n = 561) | |||
Age, years | 55.29 ± 11.52 | 60.26 ± 9.86 | 57.49 ± 11.10 | < 0.001 |
Number of pregnancies | 1.31 ± 2.28 | 1.92 ± 2.43 | 1.58 ± 2.37 | < 0.001 |
Number of abortions | 0.22 ± 0.68 | 0.28 ± 0.66 | 0.22 ± 0.68 | 0.126 |
Number of children | 1.26 ± 2.18 | 1.83 ± 2.32 | 1.51 ± 2.26 | < 0.001 |
Breast feeding duration, months | 20.23 ± 38.84 | 29.43 ± 47.19 | 24.28 ± 42.95 | < 0.001 |
Tumor size, cm | 3.15 ± 1.69 | 2.87 ± 1.53 | 3.02 ± 1.63 | < 0.001 |
Duration of sports activity, h/week | 0.55 ± 2.15 | 0.79 ± 1.87 | 0.66 ± 2.03 | 0.042 |
Breast side involvement, no. (%) | ||||
Left | 387 (54.4) | 285 (50.8) | 662 (52) | 0.208 |
Right | 325 (45.6) | 276 (49.2) | 601 (47) | |
Hormone replacement therapy, no. (%) | ||||
Yes | 5 (0.7) | 5 (0.9) | 10 (0.8) | 0.704 |
No | 707 (99.3) | 556 (99.1) | 1263 (99.2) | |
Diabetes, no. (%) | ||||
Yes | 55 (7.7) | 75 (13.4) | 130 (10.2) | 0.001 |
No | 657 (92.3) | 486 (86.6) | 1143 (89.8) | |
History of breast disease, no. (%) | ||||
Yes | 14 (2) | 9 (1.6) | 23 (1.8) | 0.630 |
No | 698 (98) | 552 (98.4) | 1250 (98.2) | |
History of breast operation, no. (%) | ||||
Yes | 5 (0.7) | 7 (1.2) | 12 (0.9) | 0.317 |
No | 707 (99.3) | 554 (98.8) | 1261 (99.1) | |
Family Hx of breast cancer, no. (%) | ||||
Yes | 73 (10.3) | 76 (13.5) | 149 (11.7) | 0.69 |
No | 639 (89.7) | 485 (86.5) | 1124 (88.3) | |
Family Hx of other cancers, no. (%) | ||||
Yes | 121 (17) | 124 (22.1) | 245 (19.2) | 0.022 |
No | 591 (83) | 437 (77.9) | 1028 (80.8) | |
Smoking, no. (%) | ||||
Yes | 5 (0.7) | 2 (0.4) | 7 (0.5) | 0.408 |
No | 707 (99.3) | 559 (99.6) | 1266 (99.5) | |
Waterpipe use, no. (%) | ||||
Yes | 26 (3.7) | 26 (4.6) | 52 (4.1) | 0.379 |
No | 686 (96.3) | 535 (95.4) | 1221 (95.9) | |
Sports activity, no. (%) | ||||
Yes | 87 (12.2) | 104 (18.5) | 191 (15) | 0.002 |
No | 626 (87.8) | 457 (81.5) | 1082 (85) | |
Regular sports activity, no. (%) | ||||
Yes | 32 (4.5) | 47 (8.4) | 79 (6.2) | 0.004 |
No | 680 (95.5) | 514 (91.6) | 1194 (93.8) | |
Lymph node management, no. (%) | ||||
AND | 578 (81.2) | 506 (90.2) | 1084 (85.2) | < 0.001 |
SLNB | 52 (7.3) | 13 (2.3) | 65 (5.1) | |
Both | 40 (5.6) | 3 (0.5) | 43 (3.4) | |
None | 42 (5.9) | 39 (7) | 81 (6.4) | |
In situ component, no. (%) | ||||
Yes | 365 (51.3) | 191 (34) | 556 (43.7) | < 0.001 |
No | 347 (48.7) | 370 (66) | 717 (56.3) | |
Tumor necrosis, no. (%) | ||||
Yes | 297 (41.7) | 132 (23.5) | 429 (33.7) | < 0.001 |
No | 415 (58.3) | 429 (76.5) | 844 (66.3) | |
Chemotherapy before surgery, no. (%) | ||||
Yes | 60 (8.4) | 49 (8.7) | 109 (8.6) | 0.846 |
No | 652 (91.6) | 512 (91.3) | 1164 (91.4) | |
Chemotherapy after surgery, no. (%) | ||||
Yes | 695 (97.6) | 541 (96.4) | 1236 (97.1) | 0.214 |
No | 17 (2.4) | 20 (3.6) | 37 (2.9) | |
Radiotherapy, no. (%) | ||||
Mastectomy with radiotherapy | 431 (60.5) | 265 (47.2) | 696 (54.7) | < 0.001 |
Mastectomy without radiotherapy | 46 (6.5) | 123 (21.9) | 169 (13.3) | |
BCS with radiotherapy | 221 (31) | 172 (30.7) | 393 (30.9) | |
BCS without radiotherapy | 14 (2) | 1 (0.2) | 15 (1.2) | |
Hormone therapy, no. (%) | ||||
Yes | 607 (85.3) | 503 (89.7) | 1110 (87.2) | 0.019 |
No | 105 (14.7) | 58 (10.3) | 163 (12.8) | |
Stage, no. (%) | ||||
0 | 84 (11.8) | 116 (20.7) | 200 (15.7) | < 0.001 |
1 | 248 (34.8) | 302 (53.8) | 550 (43.2) | |
2 | 314 (44.1) | 126 (22.5) | 440 (34.6) | |
3 and 4 | 66 (9.3) | 17 (3) | 83 (6.5) | |
Histological grade, no. (%) | ||||
1, 2 | 585 (82.2) | 511 (91.1) | 1096 (86.1) | < 0.001 |
3 | 127 (17.8) | 50 (8.9) | 177 (13.9) | |