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Table 1 Characteristics of inflammatory bowel disease patients and controls in the case-control study

From: Assessment of thyroid cancer risk in more than 334,000 patients with inflammatory bowel disease: a case-control study and a meta-analysis

 

IBD

Control

P value

Total (n)b

1392

1392

Male (n)

634

658

0.362

Age (years)b

37.0 ± 5.8

36.7 ± 5.8

0.454

BMI (kg/m2)a

23.2 ± 4.3

22.4 ± 4.3

< 0.001

History of smoking (n)

604

296

< 0.001

History of drinking (n)

410

395

0.531

History of iodized salt intaking (n)

754

708

0.081

History of radiation exposure (n)

251

14

< 0.001

History of benign thyroid nodule (n)

1064

570

< 0.001

Family history of TC (n)a

135

22

< 0.001

Age at diagnosis of IBD (years)a

26.9 ± 6.3

Duration of IBD on admission (years)

10.1 ± 2.8

Extraintestinal manifestations (n)

708

5-ASA treatment (n)a

1334

PTC development (n)a

11

3

0.032

  1. aBMI Body mass index, IBD inflammatory bowel disease, 5-ASA 5-aminosalicylic acid, PTC papillary thyroid carcinoma, TC thyroid cancer
  2. bCategorical and continuous variables were separately showed by frequency and mean ± standard deviation