Table 2 DFS results
Variables | n | % | 5-year DFS (%) | p value (log-rank test) | Univariate analysis (HR, 95% CI) | Multivariate analysis (HR, 95% CI) |
|---|---|---|---|---|---|---|
Sex | 0.0139 | |||||
M | 98 | 48.52 | 65.31 | |||
F | 104 | 51.48 | 81.73 | 0.5038 (0.2939–0.8639) | ||
ASA | 0.4824 | |||||
1 | 1 | 0.51 | ||||
2 | 73 | 37.63 | 71.23 | |||
3 | 113 | 58.25 | 76.11 | 0.9383 (0.5326–1.6531) | ||
4 | 7 | 3.61 | 71.43 | 2.2056 (0.2657–18.3117) | ||
5 | 0 | 0 | ||||
Surgical indication | 0.0065 | |||||
Occlusion | 157 | 77.72 | 73.89 | |||
Perforation | 13 | 6.44 | 46.15 | 2.9382 (0.8069–10.6997) | ||
Bleeding | 23 | 11.39 | 91.3 | 0.3116 (0.1368–0.7099) | ||
Other | 9 | 4.45 | 66.67 | 1.438 (0.3631–5.6956) | ||
Type of surgery | 0.7739 | |||||
Right hemicolectomy | 81 | 40.1 | 77.78 | |||
Left hemicolectomy | 19 | 9.41 | 63.16 | 1.5884 (0.6262–4.0293) | ||
Sigmoidectomy | 43 | 21.29 | 76.74 | 1.2044 (0.5777–2.5113) | ||
Segmental resection | 33 | 16.34 | 69.7 | 1.4012 (0.6457–3.0406) | ||
Hartmann | 17 | 8.42 | 70.59 | 1.7488 (0.5734–5.3333) | ||
Other | 9 | 4.45 | 66.67 | 1.8544 (0.4404–7.8083) | ||
Surgeon experience | 0.1181 | |||||
Expert | 164 | 81.19 | 63.16 | |||
Not expert | 38 | 18.81 | 76.22 | 0.6192 (0.3081–1.2443) | ||
Istotype | 0.2991 | |||||
Adenocarcinoma NOS | 122 | 60.4 | 74.59 | |||
Carcinoma with mucinous component | 39 | 19.31 | 69.23 | 1.2165 (0.5973–2.4776) | ||
Mucinous carcinoma | 28 | 13.86 | 78.57 | 0.7532 (0.3477–1.6315) | ||
Signet ring cells carcinoma | 2 | 0.99 | 50 | 5.2445 (0.06004–458.1240) | ||
Undifferentiated carcinoma | 0 | 0 | ||||
Mixed | 4 | 1.98 | 50 | 2.0194 (0.2771–14.7187) | ||
Other | 7 | 3.46 | 85.71 | 0.4487 (0.1164–1.7303) | ||
G | 0.2498 | |||||
1 | 8 | 4.06 | 87.5 | |||
2 | 144 | 73.1 | 75.69 | 2.0746 (0.5407–7.9603) | ||
3 | 45 | 22.84 | 68.89 | 3.2203 (0.7561–13.7156) | ||
T | 0.0003 | |||||
1 | 0 | 0 | ||||
2 | 7 | 3.46 | 85.71 | |||
3 | 134 | 66.34 | 81.34 | 1.3148 (0.3095–5.5851) | ||
4a | 43 | 21.29 | 51.16 | 4.2641 (0.9084–20.0169) | ||
4b | 18 | 8.91 | 66.67 | 2.4171 (0.4551–12.8374) | ||
Stage | 0.0067 | |||||
I | 4 | 1.98 | 75 | |||
II | 104 | 51.48 | 82.69 | 0.7248 (0.1144–4.5923) | ||
III | 94 | 46.53 | 63.83 | 1.7553 (0.2743–11.2331) | ||
Number of examined lymph nodes | 0.3275 | |||||
≥ 12 | 159 | 78.71 | 81.70 | |||
< 12 | 43 | 21.29 | 71.70 | 1.4498 (0.7441–2.8248) | ||
N | 0.0007 | |||||
0 | 108 | 53.46 | 82.41 | |||
1 | 61 | 30.2 | 68.85 | 1.9121 (1.0413–3.5111) | p = 0.0729 | |
1.8505 (0.9478–3.6131) | ||||||
2 | 33 | 16.34 | 54.55 | 3.4804 (1.5203–7.9677) | p = 0.0022 | |
3.13 (1.5150–6.4668) | ||||||
LNR | 0.0001 | |||||
0 | 120 | 59.41 | 80.83 | |||
1 | 49 | 24.26 | 71.43 | 1.5172 (0.8051–2.8592) | ||
2 | 33 | 16.34 | 51.52 | 3.7601 (1.5941–8.8694) | ||
LODDS | 0.0001 | |||||
0 | 89 | 44.06 | 82.02 | |||
1 | 80 | 39.6 | 73.75 | 1.5093 (0.8499–2.6803) | ||
2 | 33 | 16.34 | 51.52 | 4.0509 (1.6798–9.7690) |