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Table 2 Baseline demographics and disease characteristics

From: Assessment of denosumab treatment effects and imaging response in patients with giant cell tumor of bone

 

Overall (N = 190)

Sex, n (%)

 Female

105 (55)

 Male

85 (45)

Age, median (Q1, Q3), years

33 (26, 43)

ECOG performance statusa, n (%)

 0

106 (56)

 1

76 (40)

 2

6 (3)

Previous treatment

 Resection/surgery

132 (70)

 Bisphosphonates

38 (20)

 Radiotherapy

37 (20)

 Chemotherapy

21 (11)

GCTB disease type, n (%)

 Recurrent unresectable

92 (48)

 Primary unresectable

43 (23)

 Recurrent resectable

29 (15)

 Primary resectable

26 (14)

Location of target lesionb, n (%)

 Pelvis/sacrum

61 (32)

 Lower extremities

39 (21)

 Lung

38 (20)

 Spine

18 (10)

 Upper extremities

17 (9)

 Otherc

11 (6)

 Skull/neck

5 (3)

 Missing

1 (1)

  1. Q quartile, ECOG Eastern Cooperative Oncology Group, GCTB giant cell tumor of bone
  2. aECOG missing for two patients
  3. bBased on case report form
  4. cIncludes other soft tissue and bone sites