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Table 4 Correlation between radiological response and OS

From: Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG0304

 

5-year OS of CR/PR/MR (95% CI)

5-year OS of SD/PD (95% CI)

HR (95% CI)

p value

C-index (95% CI)

RECIST

91.7% (53.9%–98.8%)

82.5% (69.8%–90.2%)

1.37 (0.38–4.97)

0.63

0.50 (0.15–0.86)

Modified RECIST

93.3% (61.3%–99.0%)

81.5% (68.3%–89.6%)

1.00 (0.28–3.65)

1.00

0.59 (0.25–0.94)

WHO

93.3% (61.3%–99.0%)

81.5% (68.3%–89.6%)

1.00 (0.28–3.65)

1.00

0.59 (0.25–0.94)

JOA

84.0% (62.8%–93.7%)

84.1% (69.5%–92.1%)

1.59 (0.53–4.72)

0.40

0.57 (0.29–0.86)

Modified Choi

81.5% (61.1%–91.8%)

85.7% (70.9%–93.3%)

1.99 (0.67–5.93)

0.21

0.64 (0.39–0.90)

  1. OS overall survival, CR complete response, PR partial response, MR minor response, SD stable disease, PD progressive disease, HR hazard ratio, c-index concordance index