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Table 4 Correlation between radiological response and OS

From: Prospective comparison of various radiological response criteria and pathological response to preoperative chemotherapy and survival in operable high-grade soft tissue sarcomas in the Japan Clinical Oncology Group study JCOG0304

  5-year OS of CR/PR/MR (95% CI) 5-year OS of SD/PD (95% CI) HR (95% CI) p value C-index (95% CI)
RECIST 91.7% (53.9%–98.8%) 82.5% (69.8%–90.2%) 1.37 (0.38–4.97) 0.63 0.50 (0.15–0.86)
Modified RECIST 93.3% (61.3%–99.0%) 81.5% (68.3%–89.6%) 1.00 (0.28–3.65) 1.00 0.59 (0.25–0.94)
WHO 93.3% (61.3%–99.0%) 81.5% (68.3%–89.6%) 1.00 (0.28–3.65) 1.00 0.59 (0.25–0.94)
JOA 84.0% (62.8%–93.7%) 84.1% (69.5%–92.1%) 1.59 (0.53–4.72) 0.40 0.57 (0.29–0.86)
Modified Choi 81.5% (61.1%–91.8%) 85.7% (70.9%–93.3%) 1.99 (0.67–5.93) 0.21 0.64 (0.39–0.90)
  1. OS overall survival, CR complete response, PR partial response, MR minor response, SD stable disease, PD progressive disease, HR hazard ratio, c-index concordance index