The combined effect of non-alcoholic fatty liver disease and metabolic syndrome on colorectal carcinoma mortality: a retrospective in Chinese females

Table 3 Cox analysis of risk factors associated with recurrence

Characteristics	Univariable			Multivariable
Characteristics	HR	95% CI	p value	HR	95%CI	p value
Age (years)	1.105	0.965–1.241	0.314
BMI (kg/m²)	1.165	0.823–1.284	0.287
SBP (mmHg)	1.112	0.963–1.323	0.432
DBP (mmHg)	1.223	0.932–1.444	0.642
Triglycerides (mmol/L)	1.013	0.862–1.152	0.426
HDL (mmol/L)	1.104	1.013–1.324	0.023*	1.312	0.913–1.632	0.452
LDL (mmol/L)	1.342	0.982–1.552	0.313
Fasting glucose (mmol/L)	1.122	0.951–1.302	0.524
CEA (ng/ml)	1.123	1.032–1.452	0.014*	1.127	0.972–1.516	0.292
Differentiation	0.882	0.823–0.965	0.009*	0.904	0.832–1.176	0.128
Location	1.302	0.921–1.542	0.392
Ascending, transverse, and descending	1.000
Sigmoid	1.242	0.927–1.423	0.542
Rectum	1.132	0.912–1.402	0.356
Stage	1.322	1.095–1.932	0.011*	1.522	1.312–1.923	0.008*
I	1.000			1.000
II	1.092	0.902–1.123	0.223	1.223	0.922–1.433	0.321
III	2.123	1.232–2.873	0.001*	1.923	1.321–2.923	0.001*
MetS	1.722	1.224–2.722	0.020*	1.821	1.164–3.121	0.010*
NAFLD	1.542	0.935–2.226	0.109
Non	1.000
Mild	1.097	0.913–1.198	0.312
Moderate	1.431	0.921–2.216	0.197
Severe	1.582	0.945–2.368	0.210

NAFLD, non-alcoholic fatty livers disease, MetS metabolic syndrome, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high-density lipoprotein, LDL low-density lipoprotein
*represent the p value ≤ 0.05

ISSN: 1477-7819