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Table 2 COX regression analysis of univariate and multivariate factors influencing 2-year overall survival

From: Patient Blood Management improves outcome in oncologic surgery

 

Univariate analysis

Multivariate analysis

Parameter

HR

95% CI lower

95% CI upper

p value

HR

95% CI lower

95% CI upper

p value

Age (years)

1.03

1.015

1.039

< 0.001

1.02

1.00

1.04

0.02

Gender

0.94

0.71

1.25

0.68

 

Transfusion of RBC

3.53

2.55

4.87

< 0.001

0.77

0.39

1.54

0.46

Endocrine concomitant disease

0.98

0.71

1.33

0.87

 

GI concomitant disease

2.07

1.56

2.73

< 0.001

1.68

1.1

2.57

0.016

Hematologic concomitant disease

1.21

0.67

2.17

0.53

 

Infection concomitant disease

0.95

0.60

1.49

0.81

Cardiovascular concomitant disease

0.94

0.71

1.25

0.68

Renal concomitant disease

1.61

1.01

2.56

0.04

1.32

0.68

2.57

0.42

Pulmonic concomitant disease

0.80

0.49

1.30

0.37

 

Malignancy concomitant disease

1.63

1.24

2.16

0.001

0.88

0.52

1.48

0.62

PBM yes

0.66

0.50

0.90

0.006

0.89

0.48

1.65

0.71

Hemoglobin prior surgery

0.83

0.74

0.93

0.001

0.98

0.80

1.19

0.80

Hemoglobin post surgery

0.66

0.57

0.76

< 0.001

0.94

0.80

1.12

0.50

Hemoglobin prior surgery normal

0.49

0.32

0.75

0.001

0.48

0.31

0.74

0.001

Hb post surgery normal

1.40

0.70

2.78

0.34

 

Complications > DC IIIA without V

8.90

6.69

11.85

< 0.001

12.39

7.88

19.48

<0.001

Total number of RBCs

1.1

1.04

1.06

< 0.001

1.02

0.99

1.04

0.21

  1. HR hazard ratio, CI confidence interval, GI gastrointestinal, PBM Patient Blood Management