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Table 1 Demographic data, indications, concomitant disease, pre-surgical anemia, and numbers of RBC transfusions

From: Patient Blood Management improves outcome in oncologic surgery

 

Cumulative

N = 836

PBM−

N = 389

PBM+

N = 447

p value

Age (years)

 

64.8 ± 13.6

66.9 ± 12.4

0.019

Gender (m/f) (%)

508 (63.1%)

328 (39.2%)

216 (55.5%

173 (44.5%)

292 (65.3%)

155 (34.6%)

0.004

Indication

 Hepatobiliary

212 (25.7%)

92 (23.7%)

120 (26.8%)

0.06

 Pancreatic

80 (9.5%)

48 (12.3%)

32 (7.1%)

0.09

 CRLM

273 (32.6%)

136 (35.0%)

137 (30.6%)

1.00

 Upper GI

99 (11.8%)

54 (13.9%)

45 (10.0%)

0.42

 Intestinal

112 (13.4%)

38 (9.8%)

74 (16.6%)

0.001

 Primary other

22 (2.6%)

14 (3.6%)

8 (1.8%)

0.29

 Metastases other

38 (4.5%)

7 (1.8%)

31 (6.8%)

< 0.001

Concomitant disease

 Cardiovascular

437 (52.6%)

212 (54.5%)

225 (51.0%)

0.229

 Pulmonic

86 (10.1%)

48 (12.3%)

38 (8.3%)

0.068

 Endocrine

232 (27.6%)

97 (25.1%)

135 (29.8%)

0.090

 Gastrointestinal

319 (38.1%)

178 (45.8%)

141 (31.5%)

< 0.001

 Renal

71 (8.4%)

24 (6.1%)

47 (10.3%)

0.034

 Hematologic

50 (6.0%)

27 (7.2%)

23 (5.0%)

0.246

 Infection

84 (10.3%)

38 (9.7%)

46 (10.7%)

0.802

Hemoglobin prior to surgery (g/dl)

 

11.9 ± 2.2

12.5 ± 1.9

< 0.001

Hemoglobin before surgery normal

 

139 (35.7%)

253 (56.6%)

< 0.001

RBCs transfused per patient

 

5.5 ± 11.1

3.0 ± 6.9

< 0.001

Patients receiving at least 1 RBC

 

242 (62.4%)

180 (40.9%)

< 0.001

Complications

DC > 3a (major)

142 (16.9%)

70 (17.9%)

72 (16.0%)

0.463

  1. PBM Patient Blood Management, CRLM colorectal liver metastases, GI gastrointestinal, RBC red blood cells, DC Dindo-Clavien