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Table 3 AJCC staging system for PNETs (7th edition, 2010) [29]

From: Treatment options for PNET liver metastases: a systematic review

Stage T N M
0 Tis N0 M0
IA T1 N0 M0
IB T2 N0 M0
IIA T3 N0 M0
IIB T1–3 N1 M0
III T4 Any N M0
IV Any T Any N M1
  1. AJCC American Joint Committee on Cancer, PNET pancreatic neuroendocrine tumors, T1 < 2 cm limited to the pancreas, T2 > 2 cm limited to the pancreas, T3 tumor extends beyond the pancreas but not involving the celiac axis or SMA, T4 tumor involves celiac axis or SMA, N0 no regional lymph node metastases, N1 regional lymph node metastases, M0 no distant metastases, M1 distant metastases