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Table 3 AJCC staging system for PNETs (7th edition, 2010) [29]

From: Treatment options for PNET liver metastases: a systematic review

Stage

T

N

M

0

Tis

N0

M0

IA

T1

N0

M0

IB

T2

N0

M0

IIA

T3

N0

M0

IIB

T1–3

N1

M0

III

T4

Any N

M0

IV

Any T

Any N

M1

  1. AJCC American Joint Committee on Cancer, PNET pancreatic neuroendocrine tumors, T1 < 2 cm limited to the pancreas, T2 > 2 cm limited to the pancreas, T3 tumor extends beyond the pancreas but not involving the celiac axis or SMA, T4 tumor involves celiac axis or SMA, N0 no regional lymph node metastases, N1 regional lymph node metastases, M0 no distant metastases, M1 distant metastases