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Table 3 The relative expression of target mRNAs in the control, cisplatin, and 0.64 mg/mL SPS groups

From: Safflower polysaccharide inhibits the development of tongue squamous cell carcinoma

Groups

Bcl-2

COX-2

Bax

Cleaved caspase-3

Control (24 h)

0.713 ± 0.031

0.638 ± 0.048

0.185 ± 0.043

0.262 ± 0.081

Control (48 h)

0.720 ± 0.196

0.592 ± 0.005

0.166 ± 0.121

0.321 ± 0.021

Control (72 h)

0.693 ± 0.232

0.799 ± 0.923

0.203 ± 0.056

0.301 ± 0.044

Cisplatin (24 h)

0.585 ± 0.055

0.513 ± 0.023*

0.481 ± 0.011*

0.477 ± 0.021*

Cisplatin (48 h)

0.451 ± 0.060*

0.416 ± 0.019*

0.566 ± 0.035*

0.681 ± 0.046*

Cisplatin (72 h)

0.281 ± 0.026*

0.264 ± 0.032*

0.762 ± 0.055*

0.872 ± 0.065*

SPS (24 h)

0.423 ± 0.055*

0.408 ± 0.023*

0.314 ± 0.011*

0.585 ± 0.034*

SPS (48 h)

0.345 ± 0.060*

0.222 ± 0.019*

0.426 ± 0.035

0.822 ± 0.081*

SPS (72 h)

0.201 ± 0.026*

0.118 ± 0.032*

0.582 ± 0.055*

1.031 ± 0.092*

  1. SPS safflower polysaccharide. *P < 0.05 compared with the control group