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Table 1 Basic characteristics of included studies

From: Diffusion-weighted imaging in monitoring the pathological response to neoadjuvant chemotherapy in patients with breast cancer: a meta-analysis

Study

Year

Study design

No. of cases

Age (mean range)

Disease stages

Histologic subtype

Magnet strenth (T)

Duration of the patients (years, month)

Blind

Timing of evaluation

Agarwal

2017

NR

38

44.2(19–65)

LABC, stage II/III

IDC/DCIS

1.5 T

NR

 

Pre-NAC and after 1.3 cycles

Atuegwu

2013

NR

28

44.9 (28–67)

Stage II/III

NR

3.0 T

NR

 

Pre-NAC and after 1 cycle, and post-NAC

Belli

2011

Pro

51

48.4 (26–66)

NR

IDC/ILC

1.5 T

2007.01–2009.01

Blind

Pre-NAC and post-NAC within 4 weeks

Bufi

2014

Retro

225

47 (26–67)

Stage II/III

IDC/ILC

1.5 T

2007–2012

Blind

Pre-NAC and post-NAC within 4 weeks

Bufi

2015

Retro

225

47 (26–67)

LABC, stage II/III/IV

IDC/ILC

1.5 T

2007–2012

Blind

Pre-NAC and post-NAC within 4 weeks

Che

2016

NR

36

50.9 (27–75)

LABC

IDC/ILC

3.0 T

2014.03–2015.05

Blind

Pre-NAC and after 2 cycles

Fangberget

2010

Pro

31

50.7 (37–72)

Stage II/III/IV

IDC/ILC

1.5 T

2007.04–2008.10

Blind

Pre-NAC and after 4 cycles, and post-NAC

Fujimoto

2013

NR

56

50.9(27–70)

Stage II/III

IDC

1.5 T

2006.02–2009.12

Blind

Pre-NAC and post-NAC within 3 weeks

Li

2011

Pro

32

46 (25–63)

LABC

NR

1.5 T

2007.07–2010.07

 

Pre-NAC and after 1 cycle

Li

2015

Pro

42

46.8 (28–67)

Stage II/III

NR

3.0 T

NR

 

Pre-NAC and after 1 cycle, post-NAC

Luo

2014

Retro

71

46.1 (29–72)

NR

IDC

3.0 T

2010.03–2012.12

Blind

Pre-NAC, after 2 cycles and post-NAC

Mani

2013

NR

28

45 (28–67)

Stage II/III

NR

NR

NR

 

Pre-NAC, after 1 cycle and post-NAC

Study

Year

Study design

No. of cases

Age (mean range)

Disease stages

Histologic subtype

Magnet strenth(T)

Duration of the patients (year, months)

Blind

Timing of evaluation

Park

2010

Retro

53

43.7 (24–65)

Stage II/III

IDC/ILC

1.5 T

2007.03–2008.05

Blind

Pre-NAC and after 3 cycles

Park

2011

Retro

34

44 (27–60)

LABC

IDC/ILC

1.5 T

2007.04–2008.05

Blind

Pre-NAC and after 3–6 cycles

Richard

2013

Retro

118

53.2 (23–83)

LABC, stage II/III/IV

IDC/ILC

1.5 T

2008.07–2011.05

Blind

Pre-NAC and post-NAC less than 2 weeks

Sharma

2009

Retro

56

48.5 (25–75)

LABC

IDC

1.5 T

2003.12–2006.12

 

Pre-NAC and after 1, 2, 3 cycles

Shin

2012

Retro

90

46 (24–68)

Stage I/II/III

IDC/ILC

1.5 T

2009.01–2011.05

 

Pre-NAC and post-NAC

Weis

2015

Retro

33

46 (28–67)

Stage II/III

NR

3.0 T

NR

 

Pre-NAC, after 1 cycle and post-NAC

Woodhams

2010

NR

69

NR

NR

IDC/ILC

1.5 T

2005.01–2008.10

Blind

Pre-NAC, after 4 cycles the post-NAC

Xu

2017

NR

174

45.7 (28–64)

LABC, stage II/III

IDC/ILC

3.0 T

2011.09–2014.12

Blind

Pre-NAC, after 1 cycle and post-NAC

  1. LABC locally advanced breast cancer; IDL invasive ductal carcinoma; ILC invasive lobular carcinoma; Pro prospective; Retro retrospective; NR not reported