Fig. 3
From: Genomic characterization of colitis-associated colorectal cancer
Comparison of the frequency of genetic alterations in UC and CD. The frequency of genetic alterations shares many features between UC and CD, but there are also some differences between the two. TP53 mutations are the most commonly occurring mutations in UC and CD. APC and IDH alterations are significantly more frequent in CD than in UC. UC ulcerative colitis, CD Crohn’s disease, APC adenomatous polyposis coli, KRAS Kirsten rat sarcoma viral oncogene homolog, SMAD4 SMAD family member 4