From: Schwannoma of the colon and rectum: a systematic literature review
Characteristics | |
---|---|
Number | 95 |
Age | 61.2 years, range 14–95, median 64 years |
Sex | |
Male | 40 (41.7%) |
Female | 56 (58.3%) |
Presenting symptom | |
Asymptomatic | 27 (28.1%) |
Rectal bleeding | 22 (22.9%) |
Fecal occult blood | 8 (8.3%) |
Abdominal pain | 15 (15.6%) |
Constipation | 7 (7.3%) |
Tenesmus | 7 (7.3%) |
↗ Abdominal girth | 2 (2.1%) |
NA | 14 (14.6%) |
Location | |
Cecum and right colon | 29 (30.2%) |
Transverse colon | 5 (5.2%) |
Sigmoid | 27 (28.1%) |
Left colon | 8 (8.3%) |
Rectum | 21 (21.9%) |
Appendix | 1 (1%) |
NS | 5 (5.2%) |
Colonoscopy | 73 (76%) |
Smooth submucosal mass | 41 (56.2%) |
Ulcerated submucosal mass | 5 (6.8%) |
Submucosal polyp | 15 (20.5%) |
Intraluminal mass | 6 (8.2%) |
Polypoid | 3 (4.1%) |
Others | 3 (4.1%) |
Imaging | 46 (48%) |
CT-SCAN | 35 (76%) |
Well circumscribed | 13 (37.1%) |
Homogenous enhancement | 12 (34.3%) |
Central necrosis | 1 (1%) |
EUS: hypo-echoic mass | 7 (7.3%) |
FDG-PET | 4 (4.2%) |
Hyper | 3 (3.1%) |
Size (cm) | 3.78 cm, range 0.3–28, median 3 cm |
Diagnosis | |
Endoscopy | 23 (24%) |
Post-surgery | 71 (74%) |
Type of surgery | |
Laparoscopic | 11 (11.5%) |
Open | 58 (60.4%) |
Endoscopic | 15 (15.6%) |
Transanal | 7 (7.3%) |
NA | 5 (5.2%) |
Extent of surgery | |
Classical segmental | 65 (67.7%) |
Wedge | 3 (3.1%) |
Endo-luminal | 23 (24%) |
Tumor markers | |
S100 | 94 (97.9%) |
Vimentin | 13 (13.5%) |
GFAP | 5 (5.2%) |
CD-34 | 2 (2.1%) |
CD-68 | 1 (1%) |
Antonini type | 26 (27.1%) |
A | 15 (57.7%) |
B | 6 (23.1%) |
A, B | 5 (19.2%) |
Mitosis | |
Ki-67% | 5 (5.2%) |
MIB-1 | 6 (6.3%) |
Low mitosis | 30 (31.3%), mean 2.1/50, median 1/50 |
NA | 55 (57.3%) |
LN | |
NA | 85 (88.5%) |
Negative | 11 (11.5%) |
Aggressiveness | |
Benign | 93 (96.9%) |
Malignant | 3 (3.1%) |