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Table 1 Clinico-pathologic features of squamous cell carcinoma head and neck (n = 115)

From: Immunohistochemical expression of epidermal growth factor receptor (EGFR) in South Asian head and neck squamous cell carcinoma: association with various risk factors and clinico-pathologic and prognostic parameters

Characteristic

Frequency (%)

Age(years)a

51.95 ± 12.62

Age groups

 ≤ 30 years

4 (3.5)

 31–50 years

57 (49.6)

 > 50 years

54 (47)

Gender

 Male

85 (73.9)

 Female

30 (26.1)

History of pan (n = 44)

 Yes

27 (61.4)

 No

17 (38.6)

History of smoking(n = 44)

 Yes

4 (9.1)

 No

40 (90.9)

History of alcohol (n = 44)

 Yes

1 (2.3)

 No

43 (97.7)

Location of tumor

 Oral cavity

79 (68.7)

 Lip

3 (2.6)

 Tongue

29 (25.2)

 Soft palate

4 (3.5)

Tumor size (cm)a

3.21 ± 1.74

Tumor stage

 T1

31 (27)

 T2

54 (47)

 T3/T4

30 (26.1)

Depth of invasion (cm)a

1.11 ± 0.74

Depth of invasion

 < 2 cm

98 (85.2)

 ≥ 2 cm

17 (14.8)

Nodal stage

 No

63 (54.8)

 N1

17 (14.8)

 N2a

0 (0)

 N2b

31 (27)

 N2c

3 (2.6)

 N3

1 (0.9)

Extranodal extention

 Not present

85 (73.9)

 Present

30 (26.1)

Histological subtypes

 Non-keratinizing

17 (14.8)

 Keratinizing

65 (56.5)

 Non-keratinizing with maturation

33 (28.7)

Histologic grade

 Grade-I

31 (27)

 Grade-II

71 (61.7)

 Grade-III

13 (11.3)

Lymphovascular invasion

 Not present

114 (99.1)

 Present

1 (0.9)

Perineural invasion

 Not present

99 (86.1)

 Present

16 (13.9)

Radiation (n = 45)

 Yes

25 (55.6)

 No

20 (44.4)

Chemotherapy (n = 45)

 Yes

24 (53.3)

 No

21 (46.7)

Recurrence (n = 45)

 Yes

23 (51.1)

 No

22 (48.9)

  1. aMean ± SD