A comparison of the operative outcomes of D1 and D2 gastrectomy performed at a single Western center with multiple surgeons: a retrospective analysis with propensity score matching

Table 4 Cox proportional hazards model on prognostic factors for patients undergoing gastrectomy with D1/D1+ or D2 lymphadenectomy

		Univariable Cox regression analysis			Multivariable Cox regression analysis
Parameters		HR	95%CI	p	HR	95%CI	p
Before PSM
Age	≥ 70/< 70	1.172	0.721–1.907	0.521
Gender	F/M	1.045	0.622–1.756	0.867
BMI	< 30/≥30	1.138	0.673–1.924	0.629
Hemoglobin level	≤ 100/> 100	1.682	0.854–3.314	0.133
Tumor location	Proximal, middle/Distal	1.608	0.948–2.728	0.078
TNM stage (AJCC classification)	III, IV/ I, II	3.925	2.402–6.414	0.000*	3.519	2.067–5.993	0.000*
Chemotherapy	Yes/No	1.205	0.740–1.963	0.453
Lymphadenectomy type	D1/D1+/D2	1.338	0.787–2.272	0.282
Gastrectomy type	Total/Partial	1.803	1.102–2.949	0.019*
^aOverall complication	Yes/No	3.169	1.895–5.298	0.000*	2.971	1.714–5.149	0.000*
After PSM
Age	≥ 70/< 70	1.666	0.714–3.881	0.237
Gender	M/F	1.069	0.416–2.744	0.890
BMI	< 30/≥ 30	3.463	0.808–14.840	0.094
Hemoglobin level	≤ 100/> 100	1.596	0.542–4.701	0.396
Tumor location	Proximal, middle/Distal	1.305	0.572–2.981	0.527
TNM stage (AJCC classification)	III, IV/ I, II	6.627	2.640–16.638	0.000*	4.218	1.560–11.407	0.005*
Chemotherapy	Yes/No	1.318	0.573–3.034	0.516
Lymphadenectomy type	D1/D1+/D2	3.490	1.308–9.311	0.013*	4.353	1.511–12.541	0.006*
Gastrectomy type	Total/Partial	2.577	1.074–6.184	0.034*	2.883	0.846–9.829	0.091
^aOverall complication	Yes/No	4.480	1.901–10.560	0.001*	3.849	1.342–11.040	0.012*

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