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Table 6 Cox models measured incidence densities and hazard ratio of overall survival

From: The diagnostic ureteroscopy before radical nephroureterectomy in upper urinary tract urothelial carcinoma is not associated with higher intravesical recurrence

  N Total person-year Case per 1000 person-year Incident rate Crude HR (95% CI) p-value adjust HR (95% CI) p-value
Main Effect
 URS- (Ref.) 2,634 6,941 531 (20.16%) 76.50 1 (Ref.)   1 (Ref.)  
 URS+ 3,079 8,195 568 (18.45%) 69.31 0.907 (0.81 – 1.02) 0.108 0.919 (0.82 – 1.04) 0.164
Baseline Patient Demographic Characteristics
 Gender
  Female (Ref.) 3,241 8,643 579 (17.86%) 66.99 1 (Ref.)   1 (Ref.)  
  Male 2,472 6,493 520 (21.04%) 80.08 1.191 (1.06 – 1.34) 0.004* 1.225 (1.09 - 1.38) 0.001*
 Age Categories
  <65 yr(Ref.) 2,044 5,647 266 (13.01%) 47.10 1 (Ref.)   1 (Ref.)  
  65-74 yr 2,094 5,546 410 (19.58%) 73.93 1.561 (1.34 - 1.82) <0.001* 1.597 (1.36 - 1.87) <0.001*
  >74yr 1,575 3,943 423 (26.86%) 107.28 2.245 (1.93 - 2.62) <0.001* 2.290 (1.96 – 2.68) <0.001*
 CCI score Categories
  0 (Ref.) 613 1,637 109 (17.78%) 66.57 1 (Ref.)   1 (Ref.)  
  1 462 1,209 98 (21.21%) 81.03 1.211 (0.92 – 1.59) 0.169 1.134 (0.86 – 1.49) 0.372
  2+ 4,638 12,289 892 (19.23%) 72.58 1.088 (0.89 – 1.33) 0.407 0.956 (0.78 – 1.18) 0.671
 Hypertension
  No (Ref.) 2,743 7,322 504 (18.37%) 68.83 1 (Ref.)   1 (Ref.)  
  Yes 2,970 7,814 595 (20.03%) 76.15 1.103 (0.98 – 1.24) 0.104 0.992 (0.88 – 1.12) 0.896
 Hyperlipidemia
  No (Ref.) 4,509 11,883 908 (20.14%) 76.41 1 (Ref.)   1 (Ref.)  
  Yes 1,204 3,253 191 (15.86%) 58.72 0.772 (0.66 – 0.90) 0.001* 0.777 (0.66 – 0.91) 0.002*
 DM
  No (Ref.) 4,399 11,682 825 (18.75%) 70.62 1 (Ref.)   1 (Ref.)  
  Yes 1,314 3,454 274 (20.85%) 79.32 1.122 (0.98 - 1.29) 0.099 1.141 (0.99 - 1.32) 0.072
 ESRD
  No (Ref.) 4,562 12,134 862 (18.90%) 71.04 1 (Ref.)   1 (Ref.)  
  Yes 1,151 3,002 237 (20.59%) 78.95 1.110 (0.96 - 1.28) 0.153 1.254 (1.08 - 1.46) 0.003*
  1. Crude HR relative hazard ratio, Adjusted HR adjusted hazard ratio controlling for age, gender, CCI score, Hypertension, Hyperlipidemia, diabetes and ESRD
  2. *p<0.05