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Table 5 Cox models measured incidence densities and hazard ratio of intravesical recurrence outcome

From: The diagnostic ureteroscopy before radical nephroureterectomy in upper urinary tract urothelial carcinoma is not associated with higher intravesical recurrence

  N Total person-year Case per 1000 person-year Incident rate Crude HR (95% CI) p-value adjust HR (95% CI) p-value
Main Effect
 URS- (Ref.) 2,634 6,243 392 (14.88%) 62.79 1 (Ref.)   1 (Ref.)  
 URS+ 3,079 7,261 515 (16.73%) 70.92 1.129 (0.99 - 1.29) 0.069 1.136 (1.00 - 1.30) 0.059
Baseline Patient Demographic Characteristics
 Gender
  Female (Ref.) 3,241 7,798 464 (14.32%) 59.50 1 (Ref.)   1 (Ref.)  
  Male 2,472 5,707 443 (17.92%) 77.63 1.285 (1.13 - 1.46) <0.001* 1.293 (1.13 - 1.48) <0.001*
 Age Categories
  <65 yr(Ref.) 2,044 5,028 332 (16.24%) 66.03 1 (Ref.)   1 (Ref.)  
  65-74 yr 2,094 4,994 324 (15.47%) 64.87 0.978 (0.84 - 1.14) 0.771 0.994 (0.85 - 1.16) 0.935
  >74yr 1,575 3,482 251 (15.94%) 72.09 1.067 (0.91 - 1.26) 0.440 1.087 (0.92 - 1.29) 0.334
 CCI score Categories
  0 (Ref.) 613 1,467 95 (15.50%) 64.75 1 (Ref.)   1 (Ref.)  
  1 462 1,105 68 (14.72%) 61.53 0.947 (0.69 - 1.29) 0.731 0.932 (0.68 - 1.28) 0.661
  2+ 4,638 10,932 744 (16.04%) 68.06 1.048 (0.85 - 1.30) 0.667 0.917 (0.73 - 1.15) 0.454
 Hypertension
  No (Ref.) 2,743 6,560 437 (15.93%) 66.61 1 (Ref.)   1 (Ref.)  
  Yes 2,970 6,944 470 (15.82%) 67.68 1.009 (0.89 - 1.15) 0.887 1.011 (0.88 - 1.16) 0.870
 Hyperlipidemia
  No (Ref.) 4,509 10,591 731 (16.21%) 69.02 1 (Ref.)   1 (Ref.)  
  Yes 1,204 2,913 176 (14.62%) 60.42 0.884 (0.75 - 1.04) 0.141 0.883 (0.74 - 1.05) 0.155
 DM
  No (Ref.) 4,399 10,447 686 (15.59%) 65.66 1 (Ref.)   1 (Ref.)  
  Yes 1,314 3,057 221 (16.82%) 72.29 1.098 (0.94 - 1.28) 0.227 1.152 (0.98 - 1.35) 0.085
 ESRD
  No (Ref.) 4,562 10,876 704 (15.43%) 64.73 1 (Ref.)   1 (Ref.)  
  Yes 1,151 2,628 203 (17.64%) 77.23 1.186 (1.01 - 1.39) 0.033* 1.221 (1.04 - 1.44) 0.017*
  1. Crude HR relative hazard ratio, Adjusted HR adjusted hazard ratio controlling for age, gender, CCI score, Hypertension, Hyperlipidemia, diabetes and ESRD
  2. *p<0.05