Table 1 Clinicopathological characteristics of 502 patients with upper tract urothelial carcinoma

Age(years)(mean [SD])

65.8 (11.0)

66.1 (10.1)

65.7 (11.6)

0.705

Gender

0.334

 Male (%)

220 (43.8)

85 (41.3)

135 (45.6)

 Female (%)

282 (56.2)

121 (58.7)

161 (54.4)

Smoking

0.984

 Yes (%)

105 (20.9)

43 (20.9)

62 (20.9)

 No (%)

397 (79.1)

163 (79.1)

234 (79.1)

Bladder cancer history

0.958

 Yes (%)

148 (29.5)

61 (29.6)

87 (29.4)

 No (%)

354 (70.5)

145 (70.4)

209 (70.6)

eGFR (mL/min/1.73 m2) (median [range])

49.4 (2.9-154.3)

0.544

 ≧ 60 (%)

175 (34.9)

75 (36.4)

100 (33.8)

 <60 (%)

327 (65.1)

131 (63.6)

196 (66.2)

Dialysis

0.476

 Yes (%)

76 (15.1)

34 (16.5)

42 (14.2)

 No (%)

426 (84.9)

172 (83.5)

254 (85.8)

Surgical modality

*< 0.001

 Open (%)

329 (65.5)

110 (53.4)

219 (74.0)

 Laparoscopy (%)

155 (30.9)

90 (43.7)

65 (22.0)

 Segmental resection (%)

18 (3.6)

6 (2.9)

12 (4.1)

Tumor location

0.711

 Pelvis (%)

190 (37.8)

76 (36.9)

114 (38.5)

 Ureter (%)

221 (44.0)

95 (46.1)

126 (42.6)

 Both (%)

91 (18.1)

35(17.0)

56 (18.9)

Multifocality

0.389

 Yes (%)

117 (23.3)

44 (21.4)

73 (24.7)

 No (%)

385 (76.7)

162 (78.6)

223 (75.3)

Tumor grade

0.592

 Low (%)

111 (22.1)

48 (23.2)

63 (21.3)

 High (%)

391 (77.9)

158 (76.7)

233 (78.7)

Pathologic T stage

0.319

 pTa-Tis (%)

71 (14.1)

36 (17.5)

35 (11.8)

 pT1 (%)

131 (26.1)

54 (26.2)

77 (26.0)

 pT2 (%)

127 (25.3)

47 (22.8)

80 (27.0)

 pT3 (%)

144 (28.7)

55 (26.7)

89 (30.1)

 pT4 (%)

29 (5.8)

14 (6.8)

15 (5.1)

Pathologic N

0.999

 N0 or Nx (%)

463 (92.2)

190 (92.2)

273 (92.2)

 N1-3 (%)

39 (7.8)

16 (7.8)

23 (7.8)