Table 1 Review of previously reported cases of carcinosarcoma of the salivary glands with osteosarcoma components
Reference | Age (years)/sex | Location | Histologic type of carcinoma | Histologic type of sarcoma | Metastasis/site | Histologic type of metastatic tumor | Treatment | Outcome |
|---|---|---|---|---|---|---|---|---|
Garner et al. 1989 [7] | 57/F | Parotid gland | Adenocarcinoma | Osteosarcoma, chondrosarcoma | No | (−) | Left parotidectomy and radical neck dissection | Local recurrence at 6 weeks and died |
Yamashita et al. 1990 [8] | 52/M | Submandibular gland | Adenocarcinoma, squamous cell carcinoma | Osteosarcoma, chondrosarcoma, fibrosarcoma | No | (−) | Excision and right modified neck dissection with chemotherapy | No recurrence for 5 months |
Bleiweiss et al. 1992 [9] | 64/M | Submandibular gland | Adenocarcinoma | Osteosarcoma | No | (−) | Partial mandibulectomy with radical neck dissection | Local recurrence at 4 months |
de la Torre et al. 1995 [10] | 83/F | Parotid gland | Adenocarcinoma | Osteosarcoma, chondrosarcoma | Yes/lung | NR | Wide excision | Local recurrence and lung metastasis, died after 1Â year |
Carson et al. 1995 [11] | 51/F | Parotid gland | Adenocarcinoma | Osteosarcoma | No | (−) | Total parotidectomy with chemotherapy | Local recurrence at 7 months and died at 9 months |
Gogas et al. 1999 [12] | 77/M | Submandibular gland | Salivary duct carcinoma | Osteosarcoma. chondrosarcoma, rhabdomyosarcoma | Yes/lung | NR | Wide excision with radiotherapy and chemotherapy | Lung metastasis at 3Â months |
Sironi et al. 2000 [13] | 77/M | Parotid gland | Squamous cell carcinoma, adenocarcinoma, | Osteosarcoma | Yes/NR | NR | Right total parotidectomy with radical neck dissection | Metastasis at 3Â months |
Mardi et al. 2004 [14] | 59/M | Parotid gland | Adenocarcinoma | Osteosarcoma, chondrosarcoma | NA | NA | NA | NA |
Jang et al. 2011 [15] | 67/M | Parotid gland | Adenocarcinoma | Osteosarcoma | Yes/lung | Osteosarcoma | Left parotidectomy with radiotherapy | Lung metastasis at 5Â months |
Jha et al.2017 [16] | 35/M | Parotid gland | Adenocarcinoma | Osteosarcoma | No | (−) | Total radical parotidectomy with radiotherapy | No recurrence for 12 months |
Present case | 72/M | Parotid gland | Adenocarcinoma, squamous cell carcinoma | Osteosarcoma | Yes/abdominal cavity | Osteosarcoma | Total parotidectomy with radiotherapy | Metastasis at 6Â months and died |