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Table 2 Treatment details

From: Carotid artery infusion via implantable catheters for squamous cell carcinoma of the tonsils

Stage (UICC) I III, IVA, IVB IVC
Number of cases 1 9 1
Location Tonsils Tonsils Primary tumor extending across the midline to the contralateral tonsils invading the entire soft palate three lung metastases and large lymph node metastases
Technique Intra-arterial infusion chemotherapy Intra-arterial infusion chemotherapy 1 cycle isolated thoracic perfusion
3 cycles intra-arterial infusion chemotherapy
Number of cycles 6 4–7 4
Chemotherapeutics per cycle 30 mg cisplatin, 20 mg Adriamycin, 15 mg mitomycin, 500 mg 5-FU 50 mg cisplatin, 30 mg Adriamycin, 15 mg mitomycin 100 mg cisplatin, 60 mg Adriamycin, 20 mg mitomycin
Infusion time 7–10 min 7–10 min 10 min
Chemofiltration No Venous chemofiltration with up to 4 l filtrate over 30 to 45 min for systemic detoxification Venous chemofiltration with up to 4 l filtrate over 30 to 45 min for systemic detoxification
Additional treatment Aspirin 100 mg/day for 3 months. Repeated flushing of the port catheters is not necessary. Aspirin 100 mg/day for 3 months. Repeated flushing of the port catheters is not necessary. Aspirin 100 mg/day for 3 months. Repeated flushing of the port catheters is not necessary.
Response Complete response No response, partial response or complete response depending on pretreatment, more details on table patient characteristics Complete response