From: Association of body mass index and outcomes following lobectomy for non-small-cell lung cancer
BMI < 18.5 | BMI 18.5–24.9 | BMI 25–29.9 | BMI ≥ 30 | ||||||
---|---|---|---|---|---|---|---|---|---|
Underweight | Normal | Overweight | Obesity | ||||||
n = 40 (3.3%) | n = 662 (55.3%) | n = 428 (35.7%) | n = 68 (5.7%) | ||||||
Variables | No. | % | No. | % | No. | % | No. | % | P |
Age, (years), mean (s.d.) | 61.3 ± 8.7 | 58.8 ± 9.5 | 58.6 ± 9.2 | 59.6 ± 8.3 | 0.323 | ||||
FEV1 predicted, mean (s.d.) | 83.3 ± 23.4 | 90.6 ± 18.6 | 92.2 ± 16.5 | 86.6 ± 18.8 | 0.004 | ||||
DLCO predicted, mean (s.d.) | 63.0 ± 14.7 | 87.2 ± 15.8 | 83.8 ± 15.5 | 84.7 ± 15.1 | 0.000 | ||||
Sex | 0.020 | ||||||||
Male | 33 | 82.5 | 464 | 70.1 | 281 | 65.7 | 39 | 57.4 | |
Female | 7 | 17.5 | 198 | 29.9 | 147 | 34.3 | 29 | 42.6 | |
Alcohol-drinking history | 26 | 65.0 | 339 | 51.2 | 197 | 46.0 | 31 | 45.6 | 0.069 |
Cigarette-smoking history | 27 | 67.5 | 413 | 62.4 | 233 | 54.4 | 33 | 48.5 | 0.011 |
Albumin levels (g/dL) | 0.000 | ||||||||
Normal (≥ 3.5) | 33 | 82.5 | 615 | 92.9 | 415 | 97.0 | 66 | 97.1 | |
Abnormal (< 3.5) | 7 | 17.5 | 47 | 7.1 | 13 | 3.0 | 2 | 2.9 | |
ASA score | 0.231 | ||||||||
I—no disturbance | 8 | 20.0 | 117 | 17.7 | 70 | 16.4 | 4 | 5.9 | |
II—mild disturbance | 28 | 70.0 | 498 | 75.2 | 324 | 75.7 | 56 | 82.4 | |
III—severe disturbance | 4 | 10.0 | 47 | 7.1 | 34 | 7.9 | 8 | 11.8 | |
Hypertension | 2 | 5.0 | 112 | 16.9 | 115 | 26.9 | 36 | 52.9 | 0.000 |
Diabetes mellitus | 0 | 0.0 | 51 | 7.7 | 57 | 13.3 | 12 | 17.6 | 0.000 |
Other comorbidities | 2 | 5.0 | 28 | 4.2 | 19 | 4.4 | 3 | 4.4 | 0.956 |
Type of resection | 0.031 | ||||||||
Left upper lobectomy | 8 | 20.0 | 118 | 17.8 | 80 | 18.7 | 15 | 22.1 | |
Left lower lobectomy | 9 | 22.5 | 157 | 31.7 | 96 | 22.5 | 19 | 27.9 | |
Right upper lobectomy | 15 | 37.5 | 160 | 24.2 | 135 | 31.5 | 22 | 32.4 | |
Right middle lobectomy | 0 | 0.0 | 60 | 9.1 | 24 | 5.6 | 5 | 7.4 | |
Right lower lobectomy | 8 | 20.0 | 167 | 25.2 | 93 | 21.7 | 7 | 10.3 | |
Histologic type | 0.320 | ||||||||
Adenocarcinoma | 22 | 55.0 | 387 | 58.5 | 269 | 62.9 | 47 | 69.1 | |
Squamous cell carcinoma | 18 | 45.0 | 263 | 39.7 | 150 | 35.0 | 21 | 30.9 | |
Other type | 0 | 0.0 | 12 | 1.8 | 9 | 2.1 | 0 | 0.0 | |
Tumor stage | 0.041 | ||||||||
I | 14 | 35.0 | 294 | 44.4 | 217 | 50.7 | 35 | 51.5 | |
II | 12 | 30.0 | 213 | 32.2 | 101 | 23.6 | 17 | 25.0 | |
III | 12 | 35.0 | 155 | 23.4 | 110 | 25.7 | 16 | 23.5 |