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Table 4 Factors affecting overall survival in NE and E patient groups. Kaplan-Meier (univariate) and Cox regression (multivariate) analysis

From: Surgical treatment outcomes of patients with T1-T2 gastric cancer: does the age matter when excellent treatment results are expected?

  Group NE (< 70 years) Group E (≥ 70 years)
Univariate analysis Multivariate analysis Univariate analysis Multivariate analysis
5-year OS (%) p value HR (95% CI); p value 5-year OS (%) p value HR (95% CI); p value
Sex Male 66.0 0.263 5.24 (1.26–21.79); 0.023 46.8 0.094 0.64 (0.16–2.50); 0.528
Female 70.1 57.0
BMI < 30 65.5 0.202 7.75 (1.37–43.72); 0.020 61.5 0.678 3.71 (0.69–19.69); 0.124
≥ 30 73.9 56.7
ASA score 1–2 70.6 0.190 2.01 (0.59–6.80); 0.261 59.2 0.052 1.88 (0.53–6.70); 0.326
3–4 64.6 46.0
Lymphano-dectomy D1 76.9 0.745 1.21 (0.74–1.86); 0.981 38.9 0.172 3.93 (0.37–40.80); 0.251
D2 68.7 53.3
Retrieved lymph nodes ≤ 15 73.1 0.310 1.15 (0.24–5.44); 0.854 45.9 0.443 2.89 (0.60–13.93); 0.186
> 15 67.3 53.5
Gastrectomy Total 49.4 0.001 2.32 (0.59–9.14); 0.227 34.0 0.012 10.14 (2.15–47.77); 0.003
Subtotal 76.1 56.6
Multivisceral surgery Yes 47.4 0.006 1.93 (0.38–9.78); 0.425 53.6 0.019 22.83 (0.39–132.69); 0.131
No 70.5 33.3
Postoperative complications Yes 72.7 0.425 1.57 (0.38–6.43); 0.525 21.6 0.001 3.94 (1.05–14.82); 0.042
No 66.5 61.9
Tumor invasion T1a 89.1 0.001 5.81 (1.14–29.69); 0.034 65.7 0.010 4.29 (0.39–46.19); 0.229
T1b 85.7 62.5
T2 50.0 39.4
Lymph node metastasis LNM+ 80.7 0.001 2.02 (0.66–6.18); 0.215 36.5 0.001 0.54 (0.09–3.32); 0.512
LNM- 46.5 60.3
Distant metastasis M1 0.0 0.001 4.30 (0.31–58.14); 0.271 51.9 0.001 2.20 (0.09–53.74); 0.628
M0 69.1 0.0
Tumor localization (third) Upper 49.0 0.001 2.02 (0.36–11.21); 0.419 34.6 0.298 1.04 (0.29–3.74); 0.947
Middle 71.4 55.0
Lower 73.2 52.4
Lauren classification (type) Diffuse 60.7 0.086 9.72 (1.73–54.53); 0.010 59.0 0.147 4.82 (0.99–17.41); 0.929
Mix 64.5 68.8
Intestinal 74.4 44.4
Tumor differentiation grade G1 81.5 0.037 2.21 (0.29–16.93); 0.443 68.0 0.074 3.78 (1.03–24.39); 0.910
G2 76.8 42.9
G3 62.0 54.3
Ulceration UL+ 67.1 0.901 1.51 (0.55–4.15); 0.415 56.5 0.583 2.37 (0.66–8.51); 0.184
UL- 69.6 50.7
Lymphovascular invasion LV+ 45.8 0.001 2.00 (0.61–6.51); 0.250 42.9 0.005 2.50 (0.53–11.72); 0.245
LV- 79.1   60.9
Signet ring cell carcinoma SRC+ 67.7 0.601 2.49 (0.64–9.65); 0.186 71.4 0.354 3.92 (0.12–11.99); 0.433
SRC- 60.6 50.9
Tumor size < 2 cm 84.1 0.001 1.27 (0.37–4.31); 0.693 66.1 0.010 4.09 (0.80–20.95); 0.091
≥ 2 cm 61.5 45.7