Table 4 Factors affecting overall survival in NE and E patient groups. Kaplan-Meier (univariate) and Cox regression (multivariate) analysis

Sex

Male

5.24 (1.26–21.79); 0.023

0.64 (0.16–2.50); 0.528

Female

BMI

< 30

7.75 (1.37–43.72); 0.020

3.71 (0.69–19.69); 0.124

≥ 30

ASA score

1–2

2.01 (0.59–6.80); 0.261

1.88 (0.53–6.70); 0.326

3–4

Lymphano-dectomy

D1

1.21 (0.74–1.86); 0.981

3.93 (0.37–40.80); 0.251

D2

Retrieved lymph nodes

≤ 15

1.15 (0.24–5.44); 0.854

2.89 (0.60–13.93); 0.186

> 15

Gastrectomy

Total

2.32 (0.59–9.14); 0.227

10.14 (2.15–47.77); 0.003

Subtotal

Multivisceral surgery

Yes

1.93 (0.38–9.78); 0.425

22.83 (0.39–132.69); 0.131

No

Postoperative complications

Yes

1.57 (0.38–6.43); 0.525

3.94 (1.05–14.82); 0.042

No

Tumor invasion

T1a

5.81 (1.14–29.69); 0.034

4.29 (0.39–46.19); 0.229

T1b

T2

Lymph node metastasis

LNM+

2.02 (0.66–6.18); 0.215

0.54 (0.09–3.32); 0.512

LNM-

Distant metastasis

M1

4.30 (0.31–58.14); 0.271

2.20 (0.09–53.74); 0.628

M0

Tumor localization (third)

Upper

2.02 (0.36–11.21); 0.419

1.04 (0.29–3.74); 0.947

Middle

Lower

Lauren classification (type)

Diffuse

9.72 (1.73–54.53); 0.010

4.82 (0.99–17.41); 0.929

Mix

Intestinal

Tumor differentiation grade

G1

2.21 (0.29–16.93); 0.443

3.78 (1.03–24.39); 0.910

G2

G3

Ulceration

UL+

1.51 (0.55–4.15); 0.415

2.37 (0.66–8.51); 0.184

UL-

Lymphovascular invasion

LV+

2.00 (0.61–6.51); 0.250

2.50 (0.53–11.72); 0.245

LV-

Signet ring cell carcinoma

SRC+

2.49 (0.64–9.65); 0.186

3.92 (0.12–11.99); 0.433

SRC-

Tumor size

< 2 cm

1.27 (0.37–4.31); 0.693

4.09 (0.80–20.95); 0.091

≥ 2 cm