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Table 1 Patient Characteristics. Characteristics and postoperative course of patients with and without incisional hernia after cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC)

From: Incisional hernia and its impact on health-related quality of life after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a national prospective cohort study

Characteristics Patients with incisional hernia
N = 14
Patients without incisional hernia
N = 138
Total
N = 152
P-value
Sex 0.47
 Male 6 (42.9) 46 (33.3) 52 (34.2)
 Female 8 (57.1) 92 (66.7) 100 (65.8)
Age in years (median, range) 67 (48-72) 60 (24-75) 60 (24-75) <0.01
ASA score (median, range) 2 (1-2) 2 (1-2) 2 (1-2) 0.11
Body Mass Index (median, range) 25.9 (21.3-32.0)
*n=10
24.9 (17.2-39.2)
*n=110
25.0 (17.2-39.2)
*n=120
0.66
Preoperative neoadjuvant chemotherapy 9 (64.3) 66 (48.5)
*n= 136
75 (50) 0.26
Origin of peritoneal carcinomatosis 0.93
 Pseudomyxoma peritonei 5 (35.7) 39 (28.3) 44 (29.0)
 Colorectal cancer 5 (35.7) 63 (45.7) 68 (44.7)
 Appendix cancer 3 (21.4) 30 (21.7) 33 (21.7)
 Malignant peritoneal mesothelioma 1 (7.2) 6 (4.3) 7 (4.6)
Number of involved regions of peritoneal carcinomatosis at time of CRS (No.) (median, range) 3 (1-7) 3 (0-7) 3 (0-7) 0.75
Duration of surgery (h) (median, range) 5.9 (4.0-8.0) 5.5 (1.7-16.7) 5.6 (1.7-16.7) 0.70
Postoperative complications during hospital stay 5 (35.7) 53 (38.4) 58 (38.2) 0.84
Surgical complications (events, %)**
 Fascial dehiscence 3 (21.4) 5 (3.6) 8 (5.3)  
  Early fascia dehiscence ≤30 days postoperatively requiring re-operation 1 (33.3) 3 (60.0) 4 (50.0)  
  Late fascia dehiscence >30 days postoperatively
   Treated conservatively 1 (33.3) 0 (0.0) 1 (12.5)  
   Requiring re-operation 1 (33.3) 2 (40.0) 3 (37.5)  
 Surgical site infection 0 (0.0) 0 (0.0) 0 (0.0)  
 Intraabdominal abscess requiring drainage 1 (7.1) 3 (2.2) 4 (2.6)  
 Anastomotic leak 0 (0.0) 2 (1.4) 2 (1.3)  
 Intestinal fistula 0 (0.0) 1 (0.7) 1 (0.7)  
 Pelvic abscess spontaneous emptied through vaginal stump 0 (0.0) 1 (0.7) 1 (0.7)  
 Blow out of rectal stump 0 (0.0) 1 (0.7) 1 (0.7)  
Medical complications (events, %)**
Febrilia e causa 2 (14.3) 13 (9.4) 15 (9.9)  
Pneumonia 1 (7.1) 13 (9.4) 14 (9.2)  
Pleura effusion requiring drainage 1 (7.1) 12 (8.7) 13 (8.6)  
Urinary tract infection 1 (7.1) 9 (6.5) 10 (6.6)  
Other complications*** 1 (7.1) 20 (14.5) 21 (13.8)  
30-day mortality 0 (0.0) 1 (0.7) 1 (0.7) 0.75
Hospital stay at the department (days) (median, range) 15 (13-70) 14 (10-44) 14 (10-70) 0.18
Referred to local hospital for further recreation 4 (28.6) 44 (31.9) 48 (31.6) 0.80
Received postoperative adjuvant chemotherapy 2 (14.3) 47 (34.1) 49 (32.2) 0.64
  1. *Number of patients
  2. **: Number of events are too few allowing a statistical analysis
  3. ***Other complications included: Surgical: Pancreatic fistula, bladder tamponade (in the same patient with pancreatic fistula), diaphragm rupture (after diaphragm resection), hepatic haematoma (in the same patient with diaphragm rupture), postoperative bleeding requiring re-operation, rupture of the stomach (in the patient with postoperative bleeding), bleeding pyloric ulceration, leakage from aberrant biliary tract, haemothorax treated with streptase. Medical: Lung embolus (in the same patient with pancreatic fistula and bladder tamponade), oliguria because of dehydration, atrio-ventricular blockage requiring pacemaker, transient atrial fibrillation, exacerbation of known psychiatric disease, urinary retention requiring suprapubic drainage (history with prostatism), respiratory insufficiency, atrial fibrillation requiring medical treatment