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Table 1 Patient Characteristics. Characteristics and postoperative course of patients with and without incisional hernia after cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy(HIPEC)

From: Incisional hernia and its impact on health-related quality of life after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a national prospective cohort study

Characteristics

Patients with incisional hernia

N = 14

Patients without incisional hernia

N = 138

Total

N = 152

P-value

Sex

0.47

 Male

6 (42.9)

46 (33.3)

52 (34.2)

 Female

8 (57.1)

92 (66.7)

100 (65.8)

Age in years (median, range)

67 (48-72)

60 (24-75)

60 (24-75)

<0.01

ASA score (median, range)

2 (1-2)

2 (1-2)

2 (1-2)

0.11

Body Mass Index (median, range)

25.9 (21.3-32.0)

*n=10

24.9 (17.2-39.2)

*n=110

25.0 (17.2-39.2)

*n=120

0.66

Preoperative neoadjuvant chemotherapy

9 (64.3)

66 (48.5)

*n= 136

75 (50)

0.26

Origin of peritoneal carcinomatosis

0.93

 Pseudomyxoma peritonei

5 (35.7)

39 (28.3)

44 (29.0)

 Colorectal cancer

5 (35.7)

63 (45.7)

68 (44.7)

 Appendix cancer

3 (21.4)

30 (21.7)

33 (21.7)

 Malignant peritoneal mesothelioma

1 (7.2)

6 (4.3)

7 (4.6)

Number of involved regions of peritoneal carcinomatosis at time of CRS (No.) (median, range)

3 (1-7)

3 (0-7)

3 (0-7)

0.75

Duration of surgery (h) (median, range)

5.9 (4.0-8.0)

5.5 (1.7-16.7)

5.6 (1.7-16.7)

0.70

Postoperative complications during hospital stay

5 (35.7)

53 (38.4)

58 (38.2)

0.84

Surgical complications (events, %)**

 Fascial dehiscence

3 (21.4)

5 (3.6)

8 (5.3)

 

  Early fascia dehiscence ≤30 days postoperatively requiring re-operation

1 (33.3)

3 (60.0)

4 (50.0)

 

  Late fascia dehiscence >30 days postoperatively

   Treated conservatively

1 (33.3)

0 (0.0)

1 (12.5)

 

   Requiring re-operation

1 (33.3)

2 (40.0)

3 (37.5)

 

 Surgical site infection

0 (0.0)

0 (0.0)

0 (0.0)

 

 Intraabdominal abscess requiring drainage

1 (7.1)

3 (2.2)

4 (2.6)

 

 Anastomotic leak

0 (0.0)

2 (1.4)

2 (1.3)

 

 Intestinal fistula

0 (0.0)

1 (0.7)

1 (0.7)

 

 Pelvic abscess spontaneous emptied through vaginal stump

0 (0.0)

1 (0.7)

1 (0.7)

 

 Blow out of rectal stump

0 (0.0)

1 (0.7)

1 (0.7)

 

Medical complications (events, %)**

Febrilia e causa

2 (14.3)

13 (9.4)

15 (9.9)

 

Pneumonia

1 (7.1)

13 (9.4)

14 (9.2)

 

Pleura effusion requiring drainage

1 (7.1)

12 (8.7)

13 (8.6)

 

Urinary tract infection

1 (7.1)

9 (6.5)

10 (6.6)

 

Other complications***

1 (7.1)

20 (14.5)

21 (13.8)

 

30-day mortality

0 (0.0)

1 (0.7)

1 (0.7)

0.75

Hospital stay at the department (days) (median, range)

15 (13-70)

14 (10-44)

14 (10-70)

0.18

Referred to local hospital for further recreation

4 (28.6)

44 (31.9)

48 (31.6)

0.80

Received postoperative adjuvant chemotherapy

2 (14.3)

47 (34.1)

49 (32.2)

0.64

  1. *Number of patients
  2. **: Number of events are too few allowing a statistical analysis
  3. ***Other complications included: Surgical: Pancreatic fistula, bladder tamponade (in the same patient with pancreatic fistula), diaphragm rupture (after diaphragm resection), hepatic haematoma (in the same patient with diaphragm rupture), postoperative bleeding requiring re-operation, rupture of the stomach (in the patient with postoperative bleeding), bleeding pyloric ulceration, leakage from aberrant biliary tract, haemothorax treated with streptase. Medical: Lung embolus (in the same patient with pancreatic fistula and bladder tamponade), oliguria because of dehydration, atrio-ventricular blockage requiring pacemaker, transient atrial fibrillation, exacerbation of known psychiatric disease, urinary retention requiring suprapubic drainage (history with prostatism), respiratory insufficiency, atrial fibrillation requiring medical treatment