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Table 1 GO enrichment analysis in co-expression modules

From: Identification of key gene modules for human osteosarcoma by co-expression analysis

 

Term

Gene counts

Percent

P value

Benjamini

Module 1

Cell cycle

66

0.8

1.30E−10

3.10E−07

Negative regulation of cellular protein metabolic process

28

0.4

2.80E−10

3.50E−07

Negative regulation of protein metabolic process

28

0.4

6.80E−10

5.60E−07

Negative regulation of protein ubiquitination

18

0.2

7.50E−10

4.70E−07

Anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

16

0.2

7.10E−09

3.50E−06

Module 2

Translational elongation

51

0.8

4.20E−53

8.70E−50

Translation

61

0.9

2.60E−34

2.70E−31

Generation of precursor metabolites and energy

30

0.5

2.00E−09

1.40E−06

Oxidative phosphorylation

17

0.3

3.40E−09

1.70E−06

Ribosomal large subunit biogenesis

6

0.1

2.40E−06

1.00E−03

Module 3

ATP synthesis coupled proton transport

6

0.3

9.40E−05

4.50E−02

Energy-coupled proton transport, down electrochemical gradient

6

0.3

9.40E−05

4.50E−02

Module 4

Translational elongation

14

0.7

1.40E−11

1.50E−08

Translation

18

0.9

2.00E−08

1.10E−05

Module 5

Antigen processing and presentation

12

1.7

1.30E−13

8.60E−11

Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II

8

1.1

1.50E−10

4.70E−08

Immune response

20

2.8

2.20E−10

4.70E−08

Antigen processing and presentation of peptide antigen

6

0.8

1.80E−07

2.90E−05

Antigen processing and presentation of exogenous peptide antigen

4

0.6

1.60E−05

2.10E−03