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Table 2 Clinicopathological parameters and miR-182 expression in LUSC data from TCGA database

From: Clinical value of miR-182-5p in lung squamous cell carcinoma: a study combining data from TCGA, GEO, and RT-qPCR validation

Characteristic n Relevant expression of miR-182 (log2x)
Mean ± SD t/F value p value
Tissue LUSC 338 14.4295 ± 1.16110 − 18.590a < 0.001
Non-cancerous 45 12.2828 ± 0.64852
Gender Male 254 14.4792 ± 1.14885 1.371 0.171
Female 84 14.2791 ± 1.19174
Age (years) ≤ 60 177 14.4281 ± 1.13491 − 0.023 0.982
> 60 161 14.4310 ± 1.19279
Pathologic T T1 80 14.4445 ± 1.13309 0.912b 0.435
T2 189 14.4866 ± 1.16154
T3 58 14.3072 ± 1.22759
T4 11 13.9834 ± 0.98341
T T1 + T2 269 14.4741 ± 1.15120 1.396 0.164
T3 + T4 69 14.2556 ± 1.19150
Nodes No 217 14.4176 ± 1.15198 − 0.250 0.803
Yes 121 14.4507 ± 1.18181
Metastasis No 259 14.4528 ± 1.18483 0.669 0.504
Yes 79 14.3529 ± 1.08334
Pathologic stage I 157 14.3819 ± 1.16704 0.654b 0.581
II 125 14.4825 ± 1.20539
III 50 14.4849 ± 1.05204
IV 3 13.6550 ± 0.94917
Stage I-II 282 14.4265 ± 1.18313 − 0.065 0.948
III-IV 53 14.4379 ± 1.05597
Anatomic organ subdivision L_lower 41 14.3997 ± 1.31582 0.795b 0.529
L_upper 90 14.2951 ± 1.00576
R_lower 76 14.5891 ± 1.17043
R_middle 11 14.6375 ± 1.30430
R_upper 96 14.4124 ± 1.12167
Tumor location Peripheral 73 14.3940 ± 1.12931 0.288 0.774
Central 107 14.3435 ± 1.17386
  1. Statistically significant results (p < 0.05) are indicated in bold
  2. LUSC lung squamous cell carcinoma, SD standard deviation
  3. aStudent’s t test was used for comparison between the experimental and control groups
  4. bOne-way analysis of variance (ANOVA) was used for the analysis of five groups