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Table 2 Clinicopathological parameters and miR-182 expression in LUSC data from TCGA database

From: Clinical value of miR-182-5p in lung squamous cell carcinoma: a study combining data from TCGA, GEO, and RT-qPCR validation

Characteristic

n

Relevant expression of miR-182 (log2x)

Mean ± SD

t/F value

p value

Tissue

LUSC

338

14.4295 ± 1.16110

− 18.590a

< 0.001

Non-cancerous

45

12.2828 ± 0.64852

Gender

Male

254

14.4792 ± 1.14885

1.371

0.171

Female

84

14.2791 ± 1.19174

Age (years)

≤ 60

177

14.4281 ± 1.13491

− 0.023

0.982

> 60

161

14.4310 ± 1.19279

Pathologic T

T1

80

14.4445 ± 1.13309

0.912b

0.435

T2

189

14.4866 ± 1.16154

T3

58

14.3072 ± 1.22759

T4

11

13.9834 ± 0.98341

T

T1 + T2

269

14.4741 ± 1.15120

1.396

0.164

T3 + T4

69

14.2556 ± 1.19150

Nodes

No

217

14.4176 ± 1.15198

− 0.250

0.803

Yes

121

14.4507 ± 1.18181

Metastasis

No

259

14.4528 ± 1.18483

0.669

0.504

Yes

79

14.3529 ± 1.08334

Pathologic stage

I

157

14.3819 ± 1.16704

0.654b

0.581

II

125

14.4825 ± 1.20539

III

50

14.4849 ± 1.05204

IV

3

13.6550 ± 0.94917

Stage

I-II

282

14.4265 ± 1.18313

− 0.065

0.948

III-IV

53

14.4379 ± 1.05597

Anatomic organ subdivision

L_lower

41

14.3997 ± 1.31582

0.795b

0.529

L_upper

90

14.2951 ± 1.00576

R_lower

76

14.5891 ± 1.17043

R_middle

11

14.6375 ± 1.30430

R_upper

96

14.4124 ± 1.12167

Tumor location

Peripheral

73

14.3940 ± 1.12931

0.288

0.774

Central

107

14.3435 ± 1.17386

  1. Statistically significant results (p < 0.05) are indicated in bold
  2. LUSC lung squamous cell carcinoma, SD standard deviation
  3. aStudent’s t test was used for comparison between the experimental and control groups
  4. bOne-way analysis of variance (ANOVA) was used for the analysis of five groups