Evaluation of the HOXA11 level in patients with lung squamous cancer and insights into potential molecular pathways via bioinformatics analysis

Table 2 Relationships between the HOXA11 level and clinicopathological parameters in LUSC based on the TCGA database

Clinicopathological parameters		n	Relevant expression of HOXA11 (2^-ΔCq)
Clinicopathological parameters		n	Mean ± SD	t	P value
Tissue	Adjacent non-cancerous lung tissue	18	1.209 ± 0.813	− 20.240^a	1.5855E−17
Tissue	Cancer	475	5.531 ± 2.054
Age (years)	< 60	41	5.578 ± 2.374	0.087^a	0.931
Age (years)	≥ 60	199	5.609 ± 2.080
Gender	Male	353	5.593 ± 2.049	1.123^a	0.262
Gender	Female	120	5.349 ± 2.065
Status	Dead	204	5.445 ± 2.003	− 0.799^a	0.425
Status	Alive	269	5.597 ± 2.093
Neoplasm cancer status	With tumor	108	5.335 ± 2.211	− 1.086^a	0.278
Neoplasm cancer status	Tumor-free	299	5.590 ± 2.037
M	M0	390	5.549 ± 2.069	F = 0.224^b	0.800
	M1	4	6.041 ± 2.528
	MX	73	5.431 ± 1.974
T	T1–T2	385	5.526 ± 2.029	− 0.119^a	0.906
T	T3–T4	88	5.555 ± 2.172
N	N0–N1	424	5.525 ± 2.050	F = 2.565^b	0.078
	N2–N3	45	5.780 ± 1.974
	NX	4	3.369 ± 2.596
Race	White	331	5.465 ± 2.051	F = 3.892^b	0.021*
	Asian	9	4.264 ± 2.662
	Black	28	6.304 ± 1.585
Recurrence	Distant metastasis	36	5.524 ± 2.346	F = 0.565^b	0.571
	New primary tumor	12	5.457 ± 2.031
	Locoregional recurrence	30	4.959 ± 2.135

*P < 0.05 was considered statistically significant
^aStudent’s paired or unpaired t test was used for comparison between two groups
^bOne-way analysis of variance (ANOVA) was performed

ISSN: 1477-7819