Table 2 Univariate analysis of DFS and OS for diabetic NSCLC patients
From: Prognostic value of metformin for non-small cell lung cancer patients with diabetes
DFS | OS | |||||
|---|---|---|---|---|---|---|
p value | HR | 95% CI | p value | HR | 95% CI | |
Age (years) | 0.511 | 1.563 | 1.032–1.877 | 0.104 | 1.106 | 0.948–1.753 |
< 65 | ||||||
≥ 65 | ||||||
Gender | 0.210 | 0.874 | 0.703–1.489 | 0.109 | 0.748 | 0.720–1.310 |
Female | ||||||
Male | ||||||
Smoking status | 0.355 | 1.575 | 0.998–1.981 | 0.647 | 1.171 | 0.598–1.301 |
Non-smoker | ||||||
Smoker | ||||||
Histology | 0.879 | 0.877 | 0.643–1.637 | 0.511 | 0.974 | 0.544–1.710 |
Squamous | ||||||
Non-squamous | ||||||
Tumor location | 0.105 | 0.987 | 0.774–1.021 | 0.314 | 1.014 | 0.784–1.879 |
Left | ||||||
Right | ||||||
Stage | 0.001 | 1.878 | 1.170–2.474 | 0.037 | 1.440 | 1.110–1.901 |
I | ||||||
II | ||||||
III | ||||||
Tumor recurrence | 0.513 | 1.547 | 1.104–1.987 | 0.010 | 1.754 | 1.245–2.014 |
No | ||||||
Yes | ||||||
Metformin use | 0.010 | 0.69 | 0.387–0.947 | 0.005 | 0.548 | 0.401–0.755 |
No | ||||||
Yes | ||||||