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Table 3 Meta-analysis of the diagnostic power of the combined method (combination of urine Fn with cytology)

From: Effectiveness of urine fibronectin as a non-invasive diagnostic biomarker in bladder cancer patients: a systematic review and meta-analysis

 

Test of association

Test of heterogeneity

Z test for Fn and combined method

Parameter

Estimates

95%CIs

Q

p value

I2(%)

Z

p value

Sensitivity

0.86

0.82–0.90

11.48

0.02

65.15%

3.07

0.002

Specificity

0.77

0.70–0.84

17.88

0.00

77.63%

− 2.16

0.031

DOR

21.20

14.30–31.44

20.03

0.00

80.03%

1.52

0.129

Diagnostic score

3.05

2.66–3.45

5.57

0.23

28.24%

1.32

0.187

PLR

3.82

2.87–5.08

16.61

0.00

54.36%

− 0.10

0.920

NLR

0.18

0.13–0.24

8.72

0.07

54.11%

− 2.45

0.014

AUC-ROC

0.89

0.86–0.92

   

2.75

0.006