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Fig. 4 | World Journal of Surgical Oncology

Fig. 4

From: Transcription factor FoxM1 is the downstream target of c-Myc and contributes to the development of prostate cancer

Fig. 4

FoxM1 regulated the proliferative ability of PC-3 cells. PC-3 cells were transfected with FoxM1 overexpression plasmid and small interference RNA. a The FoxM1 overexpression effect was evaluated by Western blot. b The CCK-8 assay result showed that the PC-3 cells’ proliferative ability was increased in FoxM1 overexpression group compared with control. c Ki-67 protein level was increased in FoxM1 overexpression cells by Western blot. d The interference effect was evaluated by Western blot. e The CCK-8 assay result showed that the PC-3 cells’ proliferative ability was decreased in FoxM1 knock down group compared with control. f Ki-67 protein level was decreased in FoxM1 silencing cells. (**p < 0.01)

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