Fig. 2
Comparison of LZTS2 methylation levels between LSCC malignant tissues and paired adjacent normal tissues: LZTS2 promoter methylation levels were significantly higher in LSCC tissues compared to normal tissues (n = 96, P = 1.37e−06). Stratification analyses according to smoking status indicated the difference of LZTS2 promoter methylation levels between LSCC tissues and normal tissues was more significant in smokers (n = 78, P = 4.74e−18) versus non-smokers (n = 18, P = 0.029). T tumor specimen, N normal adjacent specimen