Table 2 Comparisons between the two cohorts reported by Cucchetti et al. and Qiao et al.
Items | Cohort in Cucchetti et al.’s | External validation cohort in Qiao et al.’s | p value |
|---|---|---|---|
Origin of patients | University of Bologna (1999 to 2008) | University of Bologna (2000 to 2011) | – |
Age (years, mean ± SD) | 62.8 ± 9.9 | 63.5 ± 9.4 | 0.40 |
Male (n/N) | 193/250 | 227/293 | 0.98 |
HBV (n/N) | 65/250 | 68/293 | 0.51 |
HCV (n/N) | 164/250 | 202/293 | 0.47 |
Mean tumor size (cm, mean ± SD) | 3.7 ± 1.8 | 3.9 ± 2.1 | 0.24 |
Moderate or poor tumor differentiation (n/N) | 174/250 | 198/293 | 0.68 |
Patients with multiple tumors (n/N) | 55/250 | 60/293 | 0.75 |
Liver cirrhosis (n/N) | 250/250 | 232/293 | < 0.05 |
CTP score (class C) (%) | 9.2 | 0 | < 0.05 |
AFP > 400 ng/ml (n/N) | 25/250 | 69/293 | < 0.05 |
MVI (n/N) | 186/250 | 78/293 | < 0.05 |