Skip to main content

Table 4 Review of prognostic factors for OS and/or EFS in previous studies by univariate and multivariate analysis

From: The extremity localized classic osteosarcomas have better survival than the axial non-classics

  Vasquez et al. [9] Whelan et al. [2] Pakos et al. [15] Janeway et al. [17] Pruksakorn et al. [18] Duchman et al. [28] Min et al. [8] Faisham et al. [27] Petrilli et al. [13]
n = 73 n = 1067 n = 2680 n = 1054 n = 144 n = 2949 n = 333 n = 163 n = 209
OS + EFS OS + PFS OS OS + EFS OS OS OS OS OS + EFS
UVA MVA UVA MVA UVA MVA UVA MVA UVA MVA UVA MVA UVA MVA UVA MVA UVA MVA
Gender ns s s ns ns ns s s s s s ns
Age ns ns s s s s s ns s s ns s s
Tumor site ns s s s s s s s s s s ns
Tumor size s ns ns s s s ns
Symptom duration ns
Primary metastasis s s s s s s s s s s s s s s
Serum ALP s s s s
Serum LDH ns
Surgery type s ns s s ns s
  1. s significant, ns not significant, OS overall survival, EFS event-free survival, PFS progression-free survival, UVA univariate analysis, MVA multivariate analysis, ALP alkaline phosphatase, LDH lactate dehydrogenase